Search for dissertations about: "hemolytic activity"

Showing result 11 - 15 of 21 swedish dissertations containing the words hemolytic activity.

  2. 11. Molecular diagnosis of drug resistance in Plasmodium falciparum and virulence factors in Entamoeba histolytica

    Author : Sherwan Zindrou; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Plasmodium falciparum; dhfr gene; pyrimethamine; cycloguanil; mutations; Polymerase chain reaction; Entamoeba histolytica; hemolysins; hemolysis; virulence factors.;

    Abstract : Four species of the protozoan parasite genus Plasmodium are known to infect man. Plasmodium falciparum, the most virulent species is increasingly associated with resistance to antimalarial drugs. READ MORE

  4. 12. Development of antimicrobial peptides : Methodological aspects, design, synthesis and evaluation of a new class of antimicrobial peptides

    Author : Marie Danielsson; Anders Undén; Maria Kempe; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Abstract : A new protective group for the indole nitrogen of the amino acid tryptophan, the Boc-sarcosinoyl-sarcosinolyl (Boc-Sar-Sar) is described. This protective group shows good stability to the reaction conditions used in solid phase peptide synthesis and can be incorporated into the peptide as Fmoc-Trp(Boc-Sar-Sar)-OH. READ MORE

  5. 13. Renal cell death in urinary tract infections : role of E. coli toxins

    Author : Ming Chen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Pyelonephritis; Escherichia coli toxins; ERK; LPA; cell death; carbon monoxide; hemolysin; nitric oxide; heme oxygenase-1; dexamethasone; kidney development;

    Abstract : Febrile urinary tract infections (UTI) are common bacterial illnesses in children. Several follow up studies have shown that 10-15 % of infants with pyelonephritis will develop permanent renal damage, i.e., renal scars, which in turn may lead to chronic diseases such as hypertension and renal insufficiency. READ MORE

  6. 14. Oxidized Cladophora nanocellulose derivatives : Functionalization towards biocompatible materials

    Author : Igor Rocha; Jonas Lindh; Natalia Ferraz; Albert Mihranyan; Maria Strömme; Eva Malmström Jonsson; Uppsala universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Cladophora nanocellulose; TEMPO oxidation; periodate oxidation; sulfonation; cellulose beads; surface properties; biomaterials; cell studies; hemocompatibility;

    Abstract : Nanocellulose is a promising candidate for biomedical applications because of its enhanced mechanical properties, increased surface area and greater porosity compared to bulk cellulose.This thesis investigates the functionalization of Cladophora nanocellulose and evaluates the influence of these modifications on physicochemical properties and biocompatibility of the material. READ MORE

  7. 15. ADAMTS13 phenotype in health and disease with special reference to thrombotic thrombocytopenic purpura

    Author : Minola Manea Hedström; Lund Pediatrik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Urology; tubular cells; podocytes; kidney; plasma; ADAMTS13; thrombotic thrombocytopenic purpura; nephrology; Urologi; nefrologi; Pediatrics; Pediatri;

    Abstract : Von Willebrand factor (VWF) is synthesized and secreted by endothelial cells into the plasma as a series of multimers. VWF induces the formation of platelet plugs at sites of vascular injury and high shear stress. Biological activity is dependent on multimeric size, which is regulated in plasma by the VWF-cleaving protease ADAMTS13. READ MORE