Search for dissertations about: "heparan sulfate mimetic"
Found 3 swedish dissertations containing the words heparan sulfate mimetic.
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1. Anti-herpes simplex virus activities of sulfomannan oligosaccharide PI-88 and disulfated cyclitols
Abstract : Herpes simplex virus (HSV) initiates invasion of human cells by binding to the cell surface heparan sulfate (HS) glycosaminoglycan chains. This step is mediated by the viral envelope glycoproteins gC and/or gB. READ MORE
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2. The glycobiology of human adenovirus infections : implications for tropism and treatment
Abstract : Human adenoviruses (HAdVs) are common human pathogens, causing gastrointestinal, ocular, and respiratory infections on a regular basis. Epidemic keratoconjunctivitis (EKC) is a severe ocular infection for which no approved antivirals are available. READ MORE
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3. Interaction of herpes simplex virus with cell surface glycosaminoglycans as a target for antiviral intervention
Abstract : Herpes simplex virus (HSV) infections in humans are predominantly manifested as oral cold sores or genital ulcers. As HSV infects cells by interaction with cell surface heparan sulfate (HS) and/or chondroitin sulfate (CS), the aim of the research work presented in this thesis was to explore the possibility of antiviral intervention with compounds that mimic HS or CS. READ MORE