Search for dissertations about: "heparan sulfate"
Showing result 16 - 20 of 98 swedish dissertations containing the words heparan sulfate.
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16. Implications of Heparan Sulfate and Heparanase in Inflammatory Diseases
Abstract : Heparan sulfate (HS), an unbranched sulfated carbohydrate chain, and the HS-degrading enzyme heparanase play important roles in physiological and pathological processes during all stages of life, from early embryogenesis to ageing. Accumulated information shows that HS and heparanase are involved in inflammatory processes and associated diseases, e. READ MORE
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17. Heparan Sulfate Proteoglycans in Brain Tumor Development
Abstract : Malignant brain tumors are aggressive neoplasms that remain challenging to treat in spite of their detailed molecular characterization. Both adults and children may suffer from brain tumors, which, if not lethal, can cause severe long-term and devastating side effects. READ MORE
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18. Interaction of Heparan Sulfate with Pro- and Anti-Angiogenic Proteins
Abstract : Heparan sulfate (HS) is an unbranched and negatively charged polysaccharide of the glycosaminoglycan family, based on the repeated (GlcNAcα1-4GlcAβ1-4) disaccharide structure. The HS backbone is modified by epimerization and sulfation in various positions. READ MORE
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19. Roles of Heparan Sulfate in Amyloid-β Pathology and Hypoxia
Abstract : Heparan sulfate (HS) is a highly sulfated polysaccharide expressed on the cell surface and in the extracellular matrix, interacting with a large number of proteins. HS is implicated in human diseases, including different types of cancer and amyloid diseases such as Alzheimer's disease (AD). READ MORE
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20. Structural and Functional Analyses of Xyloside-primed Glycosaminoglycans
Abstract : Glycosaminoglycans (GAGs) are polysaccharides produced by essentially all mammalian cells. Due to their enormous structural diversity, they are involved in many biological processes both in health and disease, including all stages of tumor progression. READ MORE