Search for dissertations about: "heparan sulphate"

Showing result 1 - 5 of 22 swedish dissertations containing the words heparan sulphate.

  1. 1. Involvement of Heparan Sulphate Biosynthesis and Turnover in Cell Proliferation. A Novel Role for Nitric Oxide in Recycling of Heparan Sulphate Proteoglycans

    University dissertation from BMC Biomedical Centre, Lund University

    Author : Katrin Mani; Lunds universitet.; Lund University.; [2001]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nitrite.; nitric oxide; growth-inhibition; xyloside; glypican; heparan sulphate; Proteoglycan; glycosaminoglycan; Clinical biology; Klinisk biologi;

    Abstract : Popular Abstract in Swedish Proteoglykaner (PG), framför allt sådana som bär glykosaminoglykan-sidokedjor av heparansulfat (HS) typ, utgör multifunktionella receptorer på cellytan och i pericellulär matrix hos alla adherenta celler i högre organismer. HS-proteoglykaner är inblandade i många olika cellprocesser, bl.a. READ MORE

  2. 2. Helicobacter pylori cell surface interactions with glycosaminoglycans. Identification and characterisation of proteins binding to heparin/heparan sulphate

    University dissertation from Meeme Utt, MMDI, University of Lund, Sölvegatan 23, S-223 62 Lund, Sweden

    Author : Meeme Utt; Lunds universitet.; Lund University.; [2002]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SELDI-TOF MS; bioinformatics; proteomics; immunoblotting; 2-DE; biosensor; heparan sulphate; heparin; binding; Helicobacter pylori; cell surface; bakteriologi; Mikrobiologi; mycology; bacteriology; Microbiology; mykologi; virologi; virology;

    Abstract : Popular Abstract in Swedish Helicobacter pylori är en bakterie som orsakar såväl magkatarr, magsår som magsäckscancer. H. pylori producerar olika virulensfaktorer såsom enzymet ureas, ett cell vakuolbildande toxin (VacA), andra cytotoxiska proteiner (cagA eller pathogenicity island-associated proteins), flageller och adhesiner. READ MORE

  3. 3. On the binding of growth-promoting polyamines to proteoglycans: Implications for growth-regulation and polycation-mediated gene transfer

    University dissertation from Department of Cell and Molecular Biology, Lund University

    Author : Mattias Belting; Lunds universitet.; Lund University.; [1999]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; cationic lipid.; gene transfer; gene therapy; cell growth; polyamine transport; spermine; polyamine; growth-inhibition; heparan sulphate; dermatan sulphate; Proteoglycan; glycosaminoglycan; cytogenetics; Genetik; cytogenetik;

    Abstract : Initial investigations were directed at studying the interaction between polyamines and various glycosaminoglycans (GAGs). The polyamine spermine displayed binding to dermatan sulphate (DS) and heparan sulphate (HS) with similar (Kd, 3.9 x 10-4 M) and higher (Kd, 0.37 x 10-6 M) affinity, respectively, than to DNA. READ MORE

  4. 4. Circulating proteoglycans and glycosaminoglycans during critical illness

    University dissertation from Anaesthesiology and Intensive Care

    Author : Axel Nelson; Lunds universitet.; Lund University.; [2014]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; heparan sulphate; glycocalyx; hyaluronic acid; syndecan; permeability; antimicrobial;

    Abstract : Popular Abstract in Swedish Blodförgiftning är en spridd och svår infektion och har en hög dödlighet. Skador på blodkärlen är en viktig del i sjukdomsutvecklingen. Glykosaminoglykaner (GAG) är negativt laddade kolhydrater som bland annat förekommer på blodkärlens insida och här utgör gränsskiktet mot blodbanan. READ MORE

  5. 5. Glypican-1: Structural and functional analysis of the N-glycosylated human protein

    University dissertation from Department of Biochemistry and Structural Biology, Lund University

    Author : Wael Awad Abdelhady; Lunds universitet.; Lund University.; [2015]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Proteoglycans; glypicans; glypican-1; heparan sulphate; N-glycosylation; exostosin-proteins; X-ray crystallography; crystal dehydration; diffraction anisotropy; Small angle X-ray scattering SAXS9; protein spectroscopy;

    Abstract : Popular Abstract in English All living things somehow communicate with each other. Cell-to-cell communication, or signalling, occurs on the molecular level, regulating the body’s activities and coordinating various cell actions and is thereby valuable for realizing cell as well as system functions. READ MORE