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Showing result 1 - 5 of 58 swedish dissertations matching the above criteria.

  2. 1. Heparin-binding protein and organ failure in critical illness

    Author : Jonas Tydén; Joakim Johansson; Magnus Hultin; Jakob Walldén; Sören Berg; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heparin-binding protein; Critical care; Shock; Acute respiratory distress syndrome; Acute kidney injury; Ventilator induced lung injury; Renal clearance; Anaesthesiology; anestesiologi;

    Abstract : Background: For patients severely ill enough to require care in an intensive care unit (ICU), both the disease itself (e.g. bacteria in the blood in sepsis or fractures after trauma) and effects of the immune system can cause circulatory, pulmonary, or renal dysfunction. Leukocytes play a dominant role in the immune system. READ MORE

  4. 2. On the prognostic value of Heparin-binding protein in Sepsis

    Author : Jonas Tverring; Infektionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Sepsis; Biomarker; Heparin-binding protein HBP ; Diagnostic accuracy; added value;

    Abstract : Sepsis causes major morbidity and mortality worldwide. There is wide consensus that biomarkers have an important role in sepsis research and patient care. Heparin-binding protein (HBP) is a neutrophil-derived, proinflammatory and vascular permeability-inducing protein and a promising novel sepsis biomarker. READ MORE

  5. 3. Studies on Heparin Binding protein in bacterial infections

    Author : Adam Linder; Infektionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Infectious diseases remain a major health problem, where sepsis and other severe bacterial infections are common causes of morbidity and mortality, and are associated with high costs for the community. The importance of early and appropriate treatment of sepsis and severe bacterial infections has been underlined by many and since sepsis is more prevalent and has a higher mortality rate than for instance acute myocardial infarction, there is a need for improvement. READ MORE

  6. 4. ANTIMICROBIAL ACTIVITIES OF HISTIDINE-RICH GLYCOPROTEIN AND CATIONIC PEPTIDES

    Author : Victoria Rydengård; Lund Dermatologi och venereologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dermatologi; venereologi; venereology; Dermatology; histidine-rich glycoprotein; heparin-binding; zinc; low pH; Medicine human and vertebrates ; Medicin människa och djur ; innate immunity; antimicrobial;

    Abstract : In an environment full of potential pathogens it is of importance for organisms to mount a fast and effective defence. Antimicrobial peptides are ancient and integral effector molecules of the innate immune system. They are found in all kinds of species from bacteria to plants and animals, indicating their importance during evolution. READ MORE

  7. 5. Novel Endogenous Antimicrobial Peptides

    Author : Emma Nordahl; Lund Dermatologi och venereologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; D5; HK; C3a; HMWK; complement; heparin-binding; antibacterial; Antimicrbial peptide; AMP;

    Abstract : Antimicrobial peptides serve as a first line of defence against invading microorganisms and are an essential part of our fast innate immune system. They are ancient molecules found in all classes of life. Antimicrobial peptides rapidly kill a broad spectrum of microbes and are immunomodulatory, i.e. READ MORE