Search for dissertations about: "heparin"

Showing result 6 - 10 of 239 swedish dissertations containing the word heparin.

2. 6. Helicobacter pylori cell surface interactions with glycosaminoglycans. Identification and characterisation of proteins binding to heparin/heparan sulphate

   Author : Meeme Utt; Celiaki och diabetes; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SELDI-TOF MS; bioinformatics; proteomics; immunoblotting; 2-DE; biosensor; heparan sulphate; heparin; binding; Helicobacter pylori; cell surface; bakteriologi; Mikrobiologi; mycology; bacteriology; Microbiology; mykologi; virologi; virology;

   Abstract : Helicobacter pylori is a gastric pathogen which cause chronic type B gastritis and peptic ulcer disease. H. pylori produces virulence factors such as urease, vacuolating cytotoxin VacA, cag pathogenicity island-associated proteins, flagella and adhesins. READ MORE

4. 7. Monocytes, Tissue Factor and Heparin-coated Surfaces : Clinical and Experimental Studies

   Author : Matilda Johnell; Agneta Siegbahn; Rolf Larsson; Jesper Swedenborg; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; monocytes; tissue factor; heparin-coated surfaces; coagulation; inflammation; thrombin; cytokines; cardiopulmonary bypass; biocompatibility; migration; chemotaxis; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

   Abstract : Cardiopulmonary bypass (CPB) is associated with inflammatory response and activation of coagulation. Heparin coating of the CPB circuit is shown to improve the biocompatibility of the surface. The biological effects of a new heparin surface, the Corline Heparin Surface (CHS), prepared according to a new principle, have been studied. READ MORE

5. 8. Characterization of Surfaces Designed for Biomedical Applications

   Author : Emma Kristensen; Hans Siegbahn; Rolf Larsson; Sven Oscarsson; Uppsala universitet; []
   Keywords : Physics; heparin; photoelectron spectroscopy; phosphorylcholine; biomaterial; quartz crystal dissipation; Fysik; fysik; Physics;

   Abstract : In order to develop blood biocompatible materials a heparin surface and a phosphorylcholine (PC) functionalized polymer surface were characterized using photoelectron spectroscopy (PES). The formation of the heparin surface was studied by quartz crystal microbalance with dissipation monitoring (QCM-D). READ MORE

6. 9. Structure and Interactions of the Extracellular Matrix Protein PRELP

   Author : Eva Bengtsson; Institutionen för experimentell medicinsk vetenskap; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reumatologi; muskelsystem; Skelett; extracellular matrix; PRELP; heparin; heparan sulfate; perlecan; collagen; cell-binding; Skeleton; rheumatology locomotion; muscle system; Biochemistry; Metabolism; Biokemi;

   Abstract : This thesis describes the structure and interactions of a novel extracellular matrix protein - PRELP (proline arginine-rich end leucine-rich repeat protein). The amino acid sequence of PRELP showed that it belonged to the leucine-rich repeat (LRR) protein family in connective tissues. READ MORE

7. 10. Antithrombotic Effects of Activated Protein C and Heparins in Deep Arterial Injury

   Author : Karl Malm; Malmö Institutionen för kliniska vetenskaper; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; traumatology; Kirurgi; ortopedi; traumatologi; orthopaedics; Surgery; mutagenesis; protein S; protein C; heparin; bleeding; arterial thrombosis; animal model;

   Abstract : The investigations presented in this thesis have evaluated different strategies to prevent thrombosis in an experimental model of deep arterial injury in rats. Unfractionated heparin (UFH) is often used to prevent thrombosis in microvascular surgery and in other vascular interventions, but a major drawback of UFH is increased bleeding. READ MORE