Search for dissertations about: "hepatic metastasis"

Showing result 1 - 5 of 6 swedish dissertations containing the words hepatic metastasis.

  2. 1. Colon cancer : management and outcome in a Swedish population

    Author : Annika Sjövall; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Colonic carcinoma; Population-based study; loco-regional recurrence; hepatic metastasis; survival;

    Abstract : Colon cancer is common in Sweden, with about 3500 new cases every year. Tumours of the colon and rectum are usually addressed as an entity. Great effort has been made to improve the outcome after rectal cancer treatment with subsequent improvement of survival. READ MORE

  4. 2. Colorectal Liver Metastases : Onco-surgical Strategies & Prognostic Factors

    Author : Petter Frühling; Bengt Isaksson; Ville Sallinen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal cancer; liver metastases; chemotherapy; oncological treatment; prognostic factors; predictive model; simultaneous resection; liver-first; colorectal-first;

    Abstract : The management of patients with colorectal cancer with liver metastases has improved over the past decades. There have been significant developments in terms of surgery, local therapies, anesthesia and oncological treatment. Nevertheless, there is no consensus on what constitutes optimal treatment strategy. READ MORE

  5. 3. The importance of Cyclophilins and Mps1 in cancer

    Author : Sonia Simon Serrano; Klinisk neurofysiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cyclophilins; liver; fibrosis; HCC; cell cycle; Mps1 and mitosis;

    Abstract : Hepatic fibrosis is a pathological response to chronic liver injuries such as chronic alcohol consumption, non-alcoholic fatty liver disease (NAFLD) or chronic viral infections. No antifibrotic compound has been approved for liver fibrosis and if the cause of the chronic injury is not solved, fibrosis can progress to cirrhosis. READ MORE

  6. 4. Liver metastases from colorectal cancer. Different strategies and outcomes

    Author : Valentinus Valdimarsson; Lund Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Liver metastases; Colorectal Neoplasms; Hepatectomy; Mortality; Treatment outcome; Retrospective studies; Sweden; Registries; Volume measurements; Repeat hepatectomy; liver surgery; Functional liver volume; Repeated operation; Recurrence;

    Abstract : Patients with colorectal liver metastases (CRLM) increasingly undergo liver resections. The belief is that the resection or ablation of a tumor, when possible, is the only possibility of a cure. READ MORE

  7. 5. Mathematical model development to investigate the pharmacokinetic variability of two anticancer drugs

    Author : Martin Fransson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Pharmacokinetic variability in a population is the variability in plasma drug concentrations among individuals. It may, for instance, be caused by differences in genes coding for drug-transport proteins and metabolizing enzymes, amount of body fat, age, sex, patient compliance, diet or disease progression. READ MORE