Search for dissertations about: "hepatitis B virus"

Showing result 1 - 5 of 57 swedish dissertations containing the words hepatitis B virus.

  1. 1. Hepatitis B virus replication and integration

    Author : Simon B. Larsson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; hepatitis B virus; replication; integration; HBV DNA; HBsAg;

    Abstract : Chronic infection with hepatitis B virus (HBV) affects 240 million people worldwide and may cause liver disease including hepatocellular carcinoma (HCC). Initially patients have high levels of HBV DNA in their blood, no liver disease and express the e antigen (HBeAg). READ MORE

  2. 2. Genetic variability of hepatitis B virus in chronic infection

    Author : Charles Hannoun; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ; hepatitis B virus; mutation; genotype; phylogeny; Recombination; coinfection; interferon; response;

    Abstract : Chronic hepatitis B is a major health problem, and may lead to cirrhosis and hepatocellular carcinoma. The liver damage in hepatitis B virus (HBV) infection is considered to be a result of the immune response, and not a cytopathic effect of the virus itself. READ MORE

  3. 3. The hepatitis B virus – Insights into genetic variability, evolution and Bayesian phylogeographic inference

    Author : Mikael Ingman; Malmö Klinisk virologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hepatit B; evolutionsbiologi; fylogeni; Hepatitis B; evolutionary dynamics; Phylogeography;

    Abstract : In terms of genome size, the hepatitis B virus is the smallest virus known to infect humans and its compactness with multiple overlapping reading frames puts restraints on the emergence of mutations. In the papers included in this thesis we aimed to investigate genetic variation within the precore and core promoter region and to describe the origin, spread and diversification of HBV genotype A. READ MORE

  4. 4. Geographic and genetic diversity of hepatitis B

    Author : Erik Alestig; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hepatitis B virus; genotype; phylogeny; molecular epidemiology; sequence analysis; mutation;

    Abstract : Hepatitis B Virus (HBV) infection is a global health problem and may lead to chronic hepatitis, liver cirrhosis and hepatocellular cancer. The ability of HBV to adapt to the host environment by genetic variation has lead to the evolution of 8 established (A-H) and 2 putative genotypes (I-J), each corresponding to a rather well-defined geographical distribution. READ MORE

  5. 5. GB virus C/hepatitis G virus infection: clinical, histological and epidemiological aspects

    Author : Per Björkman; Enheten för infektionssjukdomar; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; endoscopy; nosocomial; sexual transmission; parenteral transmission; blood donor; ALT; liver disease; hepatitis; GBV-C HGV; HCV; Infections; Infektioner;

    Abstract : GBV-C/HGV is a blood-borne virus related to the hepatitis C virus. We studied GBV-C/HGV infection in different populations, its transmission, and its association with liver disease. GBV-C/HGV viraemia was detected by PCR in 19/576 blood donors. Donors with normal and elevated ALT levels had similar rates of viraemia (1. READ MORE