Search for dissertations about: "hepatitis C"

Showing result 1 - 5 of 118 swedish dissertations containing the words hepatitis C.

  1. 1. Hepatitis C virus infection a nationwide study of associated morbidity and mortality

    University dissertation from Örebro : Örebro universitet

    Author : Ann-Sofi Duberg; Örebro universitet.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HCV; hepatitis C; epidemiology; non-Hodgkin s lymphoma; NHL; multiple myeloma; primary liver cancer; HCC; mortality; inpatient care; hospitalization; MEDICINE; MEDICIN; Infektionssjukdomar; Infectious Diseases; Epidemiology; Epidemiologi; Medicin; Medicine;

    Abstract : The hepatitis C virus (HCV) was characterised in 1989. HCV was transmitted through transfusion of blood/blood products, but injection drug use is now the most common route of transmission. READ MORE

  2. 2. Design and Synthesis of Inhibitors Targeting the Hepatitis C Virus NS3 Protease Focus on C-Terminal Acyl Sulfonamides

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Robert Rönn; Uppsala universitet.; [2007]
    Keywords : Pharmaceutical chemistry; hepatitis C virus; HCV; NS3 protease inhibitor; acyl sulfonamide; bioisostere; palladium; carbonylation; microwave; molybdenum hexacarbonyl; Farmaceutisk kemi;

    Abstract : Hepatitis C is a global health problem that affects approximately 120–180 million people. This viral infection causes serious liver diseases and the therapy available suffers from low efficiency and severe side effects. Consequently, there is a huge unmet medical need for new therapeutic agents to combat the hepatitis C virus (HCV). READ MORE

  3. 3. GB virus C/hepatitis G virus infection: clinical, histological and epidemiological aspects

    University dissertation from Department of Infectious Diseases, Lund University

    Author : Per Björkman; [2001]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; endoscopy; nosocomial; sexual transmission; parenteral transmission; blood donor; ALT; liver disease; hepatitis; GBV-C HGV; HCV; Infections; Infektioner;

    Abstract : GBV-C/HGV is a blood-borne virus related to the hepatitis C virus. We studied GBV-C/HGV infection in different populations, its transmission, and its association with liver disease. GBV-C/HGV viraemia was detected by PCR in 19/576 blood donors. Donors with normal and elevated ALT levels had similar rates of viraemia (1. READ MORE

  4. 4. Discovery and evaluation of direct acting antivirals against hepatitis C virus

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Eldar Abdurakhmanov; Uppsala universitet.; [2015]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Direct acting antivirals; Hepatitis C; NS3-4A protease; NS5B polymerase; structure-based drug discovery; fragment-based drug discovery; surface plasmon resonance; Biokemi; Biochemistry;

    Abstract : Until recently, the standard therapy for hepatitis C treatment has been interferon and ribavirin. Such treatment has only 50% efficacy and is not well tolerated. The emergence of new drugs has increased the treatment efficacy to 90%. READ MORE

  5. 5. Autoimmune hepatitis in Sweden

    University dissertation from Umeå : Umeå universitet

    Author : Mårten Werner; Umeå universitet.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Autoimmune hepatitis; epidemiology; cirrhosis; prognosis; thiopurines; pregnancy; breast feeding; relapse; hepatocellular cancer; lymphoma; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Gastroenterology; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Gastroenterologi; medicin; Medicine;

    Abstract : Autoimmune hepatitis (AIH) was identified as an entity by the Swedish professor Jan Waldenström in the 1950s. It was then denoted lupoid hepatitis, characterized by liver inflammation and most often affecting young women. READ MORE