Search for dissertations about: "hepatoblastoma"

Found 3 swedish dissertations containing the word hepatoblastoma.

2. 1. Regulation of insulin-like growth factor-II in human liver

   Author : Henrik von Horn; Karolinska Institutet; Karolinska Institutet; []
   Keywords : IG17-II; IGF2; IGFBPs; liver; hepatoblastoma; GH; hypoxia;

   Abstract : Insulin-like growth factors-I and -II (IGF-I and -II) are mitogens in a number of cell types and also have insulin-like actions. IGF-II has an autocrine role in a variety of malignancies; and hypoglycemia is well documented in conditions associated with elevated IGF-II precursor forms in the circulation. READ MORE

4. 2. Genomic imprinting and DNA epigenetic modification in human liver and carcinogenesis : regulation of the IGF2 and H19 genes

   Author : Xuri Li; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Genomic imprinting, which is an non-classical genetic event discovered approximately a decade ago, has been shown to be involved in the mammalian development and several kinds of human diseases. Epigenetic modifications, such as DNA methylation, are believed to be markers functioning as the imprinting signals. READ MORE

5. 3. Congenital heart disease, genetic syndromes, and childhood cancer

   Author : Christina-Evmorfia Kampitsi; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Childhood cancer is a diverse group of rare diseases and remains a significant global concern, despite substantial improvements in survival outcomes. Yet, little is known about its etiology. READ MORE