Search for dissertations about: "hepatocyte injury"

Showing result 1 - 5 of 14 swedish dissertations containing the words hepatocyte injury.

  2. 1. Hepatocyte growth factor : Studies on local and systemic release and effects during infectious disease; in vivo and in vitro

    Author : Fariba Nayeri; Minoca Niste'r; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The interaction of mesenchymal and epithelial cells that occurs after organ injuries results in enhanced production of cytokines, such as hepatocyte growth factor (HGF). HGF is a glycoprotein with unique properties that contribute to wound healing after injuries. READ MORE

  4. 2. Hepatic ischemia-reperfusion injury

    Author : Melroy Alistair D'Souza; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Hepatic ischemia-reperfusion (I/R) injury is a complex phenomenon occuring in response to interruption of the liver’s blood and oxygen supply and the subsequent restoration of blood flow and tissue oxygenation. Techniques to reduce blood loss and other intra-operative manoeuvers during liver resection can cause hepatic I/R injury. READ MORE

  5. 3. Mechanistic analyses of hepatocyte plasticity

    Author : Nuria Oliva-Vilarnau; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Adult hepatocytes are highly plastic cells which have a molecular toolbox for efficient regeneration. Yet, end stage liver diseases are becoming an increasing clinical burden. READ MORE

  6. 4. On Leukocyte Recruitment in Cholestatic Liver Injury

    Author : Matthias Laschke; Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Leukocyte and Liver; Inflammation; Cholestasis; Endothelium;

    Abstract : Cholestasis is a frequent clinical syndrome, which is caused by a dysfunction in bile formation of the hepatocyte or from obstruction of the biliary tract. This is associated with inflammation of the liver tissue, resulting in severe liver injury. In this inflammatory process, leukocyte recruitment has emerged as a key feature. READ MORE

  7. 5. Experimental studies on the effects of hepatocyte-based liver support

    Author : Helene Lilja; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

    Abstract : Liver transplantation is limited by lack of donors and consequently there is a need to develop liver support/replacement therapies, such as hepatocyte transplantation (HcTx) and artificial livers. In the present thesis, the effects of these therapies were investigated. First, we established a technique of isolating fetal hepatocytes (FH). READ MORE