Search for dissertations about: "hepatology"

Showing result 1 - 5 of 91 swedish dissertations containing the word hepatology.

2. 1. Cancer and reconstructive surgery in Inflammatory bowel disease

   Author : Maie Abdalla; Pär Myrelid; Johan D Söderholm; Roland Andersson; Kalle Landerholm; Yves Panis; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Inflammatory bowel disease; Colorectal cancer; IRA; IPAA; Primary sclerosing cholangitis;

   Abstract : Ulcerative colitis (UC) is a chronic inflammatory disease that affects the colon. According to the literature, some thirty percent of UC patients may require a subtotal colectomy and ileostomy due to failure of medical treatment, acute toxic colitis or dysplasia/cancer diagnosis. READ MORE

4. 2. Understanding the molecular mechanisms of bile acid receptor activation for the treatment of human liver disease

   Author : Samer Al-Dury; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicinska sjukdomar; Gastroenterologi och hepatologi; FXR; IBAT; Gallsyror; Obesitas; Gallstenar;

   Abstract : Farnesoid X receptor (FXR) is a nuclear transcription factor that is activated by bile acids and regulates bile acid homeostasis, glucose and lipid metabolism. FXR activation by a ligand has been identified as a therapeutic modality for a range of liver and metabolic diseases. READ MORE

5. 3. Staging and tumor biological mechanisms of lymph node metastasis in invasive urinary bladder cancer

   Author : Firas Aljabery; Oliver Gimm; Staffan Jahnson; Ivan Shabo; Hans Olsson; Peter Söderkvist; Ralph Peeker; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : Aim: To study the possibility of detecting lymph node metastasis in locally advanced urinary bladder cancer (UBC) treated with radical cystectomy (RC) by using preoperative positron emission tomography/computed tomography (PET/CT) and peroperative sentinel node biopsy (SNB) technique. We also investigate the clinical significance of macrophage traits expression by cancer cells, M2-macrophage infiltration (MI) in tumor stroma and the immunohistochemical expression of biomarkers in cancer cells in relation to clinicopathologic data. READ MORE

6. 4. Immunogenetics of Type 1 diabetes and Celiac disease

   Author : Shehab Abdulaziz Alshiekh; Celiaki och diabetes; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; celiac disease; type 1 diabetes; children; genetics; human leukocyte antigen; next generation sequencing;

   Abstract : AbstractThe primary purpose of understanding disease etiology is to explain how a specific phenotype is determined by genotype. In pursue of this aim, exploring the diversity in DNA sequence variants that affect biomedical traits, especially those related to the onset and progression of genetically determined human disease. READ MORE

7. 5. Stent treatment of perforated duodenal ulcer - physiology and clinical aspects

   Author : Jorge Alberto Arroyo Vázquez; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Stent; Gastroscopy; Perforated duodenal ulcer; Proton Pump inhibitor; Gastric bacterial flora; Gastric pH; Pylorus; EndoFLIP™; Pyloric motility;

   Abstract : Background The incidence of perforated duodenal ulcer is decreasing but still constitutes a life-threatening complication to peptic ulcer disease. Abdominal contamination from gastric or duodenal content occurs during perforations. READ MORE