Search for dissertations about: "heterocyclic chemistry"
Showing result 1 - 5 of 41 swedish dissertations containing the words heterocyclic chemistry.
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1. On the Versatility of Microwave-Assisted Chemistry Exemplified by Applications in Medicinal Chemistry, Heterocyclic Chemistry and Biochemistry
University dissertation from Uppsala : Acta Universitatis UpsaliensisAbstract : Today, the demand for speed in drug discovery is constantly increasing, particularly in the iterative processes of hit validation and expansion and lead optimization. Irradiation with microwaves (MWs) has been applied in the area of organic synthesis to accelerate chemical reactions and to facilitate the generation of new chemical entities since 1986. READ MORE
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2. Construction of Five-Membered Heterocyclic Compounds via Radical Cyclization
University dissertation from Uppsala : Acta Universitatis UpsaliensisAbstract : This thesis describes how radical cyclization chemistry can be applied for the construction of heterocyclic compounds.In the first part, a series of electron deficient α-phenylselenenylalkenes were prepared via a PhSeCl-addition/HCl-elimination sequence. READ MORE
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3. N-Heterocyclic Carbene Catalysis in Organic Synthesis - A Green Chemistry Approach
University dissertation from ; Chalmers tekniska högskola; GothenburgAbstract : The twelve principles of green chemistry were created as a response to the multiple environmental issues caused by the release of waste from the chemical industry. The principles acts as a guide in the development of sustainable chemical processes for the syntheses of important molecules needed to sustain our living standards. READ MORE
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4. Reaction Between Grignard reagents and Heterocyclic N-oxides Synthesis of Substituted Pyridines, Piperidines and Piperazines
University dissertation from Umeå : Umeå universitetAbstract : This thesis describes the development of new synthetic methodologies for preparation of bioactive interesting compounds, e.g. substituted pyridines, piperidines or piparazines. Thesecompounds are synthesized from commercially available, cheap and easily prepared reagents, videlicet the reaction between Grignard reagents and heterocyclic N-oxides. READ MORE
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5. Palladium(0)-Catalysed Carbonylative Multicomponent Reactions Synthesis of Heterocycles and the Application of Quinolinyl Pyrimidines as Enzyme Inhibitors
University dissertation from Uppsala : Acta Universitatis UpsaliensisAbstract : Palladium-catalysed carbonylative multicomponent reactions have proven useful for the synthesis of structurally diverse compounds. Carbon monoxide serves as an atom-efficient, one-carbon building block, which allows for further structural elaboration of the carbonyl compound. READ MORE
