Search for dissertations about: "high LET"

Showing result 1 - 5 of 105 swedish dissertations containing the words high LET.

  2. 1. Cellular effects after exposure to mixed beams of ionizing radiation

    Author : Elina Staaf; Andrzej Wojcik; Siamak Haghdoost; Eva Forssell-Aronsson; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Ionizing radiation; high LET; low LET; mixed beams; combined exposure; molekylärgenetik; Molecular Genetics;

    Abstract : Mixed beams of ionizing radiation in our environment originate from space, the bedrock and our own houses. Radiotherapy patients treated with boron neutron capture therapy or with high energy photons are also exposed to mixed beams of gamma radiation and neutrons. READ MORE

  4. 2. Radiobiological investigations of proton and light ion therapy

    Author : Nina Tilly; Michael Scholz; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radiobiology; Monte Carlo method; Radiotherapy; high-energy instrumentation; Protons; Light ions; RBE; LET; Radiobiological models; Radiobiologi; medicinsk strålningsfysik; Medical Radiation Physics;

    Abstract : During the last decade, the interest in proton and light ion beam therapy has increased considerably and several new centres are planned around the world. These particles have a large advantage due to their sharp physical dose distributions as compared to conventional radiotherapy beams. READ MORE

  5. 3. Averaged linear energy transfer and other beam quality descriptors inr elation to relative biological effectiveness

    Author : Fredrik Kalholm; Niels Bassler; Iuliana Toma-Dasu; Emanuele Scifoni; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; LET; RBE; LQ-model; medicinsk strålningsfysik; Medical Radiation Physics;

    Abstract : In radiotherapy with protons, a constant relative biological effectiveness (RBE) of 1.1 is traditionally applied, i.e. protons are assumed to be 10\% more effective than photons in killing cells. READ MORE

  6. 4. Role of Non-Homologous End-Joining in Repair of Radiation-Induced DNA Double-Strand Breaks

    Author : Karin Karlsson; Bo Stenerlöw; Jörgen Carlsson; Thomas Helleday; Uppsala universitet; []
    Keywords : Molecular biology; DNA damage; DNA repair; DSB; NHEJ; DNA-PK; ionising radiation; high-LET; heat-labile sites; PFGE; Molekylärbiologi;

    Abstract : Efficient and correct repair of DNA damage, especially DNA double-strand breaks (DSBs), is vital for the survival of individual cells and organisms. Defects in the DNA repair may lead to cell death or genomic instability and development of cancer. READ MORE

  7. 5. Dosimetry and radiation quality in fast-neutron radiation therapy : A study of radiation quality and basic dosimetric properties of fast-neutrons for external beam radiotherapy and problems associated with corrections of measured charged particle cross-sections

    Author : Jonas Söderberg; Gudrun Alm Carlsson; Crister Ceberg; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neutron; Dosimetry; Radiotherapy; Monte Carlo; Microdosimetry; Cross-section; RBE; LET; Energy-loss corrections; Radiological physics; Radiofysik;

    Abstract : The dosimetric properties of fast-neutron beams with energies ≤80 MeV were explored using Monte Carlo techniques. Taking into account transport of all relevant types of released charged particles (electrons, protons, deuterons, tritons, 3He and α particles) pencil-beam dose distributions were derived and used to calculate absorbed dose distributions. READ MORE