Search for dissertations about: "high through-put"

Showing result 1 - 5 of 12 swedish dissertations containing the words high through-put.

  2. 1. A Solution Exchange Platform for Exposure of Cells to Chemical Waves

    Author : Jessica Olofsson; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; waveform synthesis; solution exchange; cell signalling; patch clamp; receptor; high through-put; microfluidics; microfabrication; channel; chemical oscillations; ion channel; poly dimethylsiloxane ; drug discovery;

    Abstract : This thesis presents the development, characterization and suggested applications of a platform for controlling the chemical environment around a cell or a cell constituent. The platform is unique in its capability to combine rapid solution switching with precise timing and access to a manifold of solution environments. READ MORE

  4. 2. Aluminium alloy development for Additive Manufacturing

    Author : Freddy Leijon; Johan Moverare; Svain Skjervold; Ehsan Ghassemali; Linköpings universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Aluminium alloys; Alloy design; Powder bed fusion; Printability; Solidification cracking; Additive manufacturability; High through put methods; Heterogeneous nucleation;

    Abstract : Powder Bed Fusion (PBF Additive Manufacturing AM have emerged as a promising manufacturing process possessing a powerful combination of characteristics. Most noticeable are the near-net-shape, short lead time and flexibility, both with regard in design freedom and in part-to-part variation. READ MORE

  5. 3. Primary Recovery of Biologically Active Compounds Using Macroporous Monolithic Hydrogels

    Author : Amro Hanora; Bioteknik; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Downstream processing; macroporous; Biologically active compounds; Biotechnology; Läkemedelsteknik och relaterad teknik; Pharmaceutical and related technologies; Polymerteknik; biopolymers; Biokemisk teknik; Polymer technology; Makromolekylär kemi; Biochemical technology; Affinity chromatography; Ion exchange chromatography; Expanded bed adsorption chromatography.; Macromolecular chemistry; High through put screening; lactica acids; Endotoxin; Plasmid DNA; Cryogel columns; Bioteknik;

    Abstract : The completion of sequencing of human and other mammalian genomes opens a new era for drug development. New approaches have been proposed for tackling diseases such as development of small molecule therapies based on understanding of human genome and proteome, new proteinous based therapies, where the therapeutic protein can inhibit or modify a certain metabolic pathway or DNA-based therapies delivering a gene into the cell (e. READ MORE

  6. 4. Normalization and analysis of high-dimensional genomics data

    Author : Mattias Landfors; Patrik Rydén; Rebecka Jörnsten; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; normalization; pre-processing; microarray; downstream analysis; evaluation; sensitivity; bias; genomics data; gene expression; spike-in data; ChIP-chip; Mathematical Statistics; matematisk statistik;

    Abstract : In the middle of the 1990’s the microarray technology was introduced. The technology allowed for genome wide analysis of gene expression in one experiment. Since its introduction similar high through-put methods have been developed in other fields of molecular biology. READ MORE

  7. 5. Microbial Communities in Boreal Peatlands : Responses to Climate Change and Atmospheric Nitrogen and Sulfur Depositions

    Author : Magalí Martí Genero; Bo Svensson; Åsa Danielsson; Torben Christensen; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; Microbial communities; methanogens; plant communities; peatland; temperature; nitrogen; long-term; field experiment; high-throughput sequencing; Microbiella samhällen; metanogener; växtsamhällen; myrar; torv; temperatur; kväve; långtid; fältexperiment; high-throughput-sekvensering;

    Abstract : Myrmarker har en stor roll i regleringen av den globala kolbalansen och koncentrationerna av koldioxid och metan i atmosfären, vilket gör dem till speciellt viktiga ekosystem ur ett klimatförandringsperspektiv. Förändringar av myrmarker genom naturlig utveckling eller antropogen påverkan kan därför få långtgående störningar av myrars klimatreglerande funktion. READ MORE