Search for dissertations about: "high-coverage genomes"

Found 3 swedish dissertations containing the words high-coverage genomes.

  2. 1. Human demographic history : Insights on the human past based on genomes from Southern through Central Africa

    Author : Gwenna Breton; Mattias Jakobsson; Carina Schlebusch; Per Sjödin; Paul Verdu; David Comas; Uppsala universitet; []
    Keywords : high-coverage genomes; Sub-Saharan Africa; demography; genetic admixture; population genetics; human evolutionary genetics; Khoe-San; rainforest hunter-gatherers; Biology with Specialisation in Human Evolution and Genetics; Biologi med inriktning mot människans evolution och genetik;

    Abstract : Evidence from paleontology, archaeology and population genetics support that modern humans originated in Africa. While the out-of-Africa event and subsequent colonization of all continents are well documented, human history in Africa at that time and before is less studied. READ MORE

  4. 2. Palaeogenomic reconstruction of woolly mammoth evolutionary history and extinction dynamics

    Author : Marianne Dehasque; Love Dalén; David Díez-del-Molino; Rike Stelkens; Rebecca N. Johnson; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; woolly mammoth; Mammuthus primigenius; extinction; Wrangel Island; ancient DNA; palaeogenomics; radiocarbon dating; structural variants; genome erosion; population structure; Systematic Zoology; zoologisk systematik och evolutionsforskning;

    Abstract : Biodiversity is declining globally. Yet, the biological and genetic processes associated with these declines on a longer timescale are still poorly understood. Ancient DNA is a powerful tool to study evolution in real-time. Despite advances in the field, there is further need for refinement of laboratory and computational techniques. READ MORE

  5. 3. Genomic analysis of the process leading up to the extinction of the woolly mammoth

    Author : Patrícia Pečnerová; Love Dalén; Mark Thomas; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; woolly mammoth; Mammuthus primigenius; extinction; Wrangel Island; ancient DNA; palaeogenetics; population genetics; genomics; genomic erosion; genetic drift; inbreeding; population size; Systematic Zoology; zoologisk systematik och evolutionsforskning;

    Abstract : Species worldwide are subject to contractions in both abundance and geographical range, and their persistence in a changing environment may thus depend on the ability to survive in small and fragmented populations. Despite the urgent need to understand how extinction works, our knowledge of pre-extinction genetic processes is limited because techniques allowing population and conservation genomics to be studied in wild threatened populations have become available only recently. READ MORE