Search for dissertations about: "high-gliadin affinity blocking peptides"

Found 1 swedish dissertation containing the words high-gliadin affinity blocking peptides.

  1. 1. Gliadin-Blocking Peptides In vitro assessment of their potential to alleviate celiac disease development

    Author : Karolina Hoffmann; Chalmers University of Technology; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; LANTBRUKSVETENSKAPER; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; AGRICULTURAL SCIENCES; high-gliadin affinity blocking peptides; Caco-2 cells; in vitro digestion; tissue transglutaminase; celiac disease; gliadin; α-amylase trypsin inhibitors;

    Abstract : This thesis work aimed to investigate the potential of synthetic peptides as agents to block wheat prolamins (gliadins) that trigger the development of symptoms in celiac disease. The first step of this investigation included selection and synthesis of peptides with high affinity to gliadins and assessment of the potential of these so-called blocking peptides to limit gliadin reactivity in vitro. READ MORE