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Showing result 1 - 5 of 11 swedish dissertations matching the above criteria.

  2. 1. Canine C-reactive protein : validation of two automated canine-specific C-reactive protein assays and studies on clinical and research applications

    Author : Anna Hillström; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Abstract : C-reactive protein (CRP) is a sensitive and specific marker of systemic inflammation in dogs, valuable for diagnosing and monitoring inflammatory diseases. The use of CRP in canine medicine has however been hampered by the lack of automated assays optimized for measuring CRP in this species. READ MORE

  4. 2. Atrial fibrillation : treatment, associated conditions and quantification of symptoms

    Author : Niklas Höglund; Steen Jensen; Milos Kesek; Karl Franklin; Juhani Koistinen; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Atrial fibrillation; cardioversion; atorvastatin; high-sensitivity C-reactive protein; symptoms; sleep apnea; kardiologi; Cardiology;

    Abstract : Background: Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia. There is a need for new pharmacological treatment strategies since the current antiarrhythmic drugs have a modest efficacy and may have severe side effects. Cardioversion (CV) of AF offers an opportunity to study related conditions in sinus rhythm (SR) and during AF. READ MORE

  5. 3. Fecal calprotectin in children with special reference to inflammatory bowel disease

    Author : Ulrika Lorentzon Fagerberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Biological markers; calcium-binding proteins; Leukocyte L1 Antigen Complex; calprotectin; acute- phase proteins; serum amyloid A; C-reactive protein; ELISA; feces; blood; children; adolescent; colitis; inflammatory bowel disease; colonoscopy; reference values; diagnosis.;

    Abstract : This thesis aims to study the clinical usefulness of fecal calprotectin as a noninvasive marker of colonic inflammation in children with suspected or confirmed chronic inflammatory bowel disease (IBD). Calprotectin, a calcium-binding protein predominantly expressed in neutrophils, is stable in feces for several days, and can be measured by an enzyme-linked immunosorbent assay. READ MORE

  6. 4. Identification of pathophysiological and prognostic biomarkers in different types of myocardial infarction

    Author : Marcus Hjort; Bertil Lindahl; Kai M. Eggers; Helge Rørvik Røsjø; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; myocardial infarction; biomarker; pathophysiology; prognosis; MINOCA; STEMI; NSTEMI; hjärtinfarkt; biomarkör; patofysiologi; prognos; MINOCA; STEMI; NSTEMI; Cardiology; Kardiologi;

    Abstract : The pathophysiological mechanisms of myocardial infarction (MI) with non-obstructive coronary arteries (MINOCA) are largely unknown. Analogous, differences in pathobiology between ST-elevation myocardial infarction (STEMI) and non-ST-elevation myocardial infarction (NSTEMI) are incompletely understood. READ MORE

  7. 5. Associations between oral biofilm, periodontal disease, and systemic health : with a focus on atherosclerosis and breast cancer

    Author : Maha Yakob; Karolinska Institutet; Karolinska Institutet; []
    Keywords : periodontal disease;

    Abstract : The general hypothesis of this series of studies was that oral infections, particularly periodontal disease, by triggering inflammatory reactions detrimentally affect systemic health where inflammations are known to play a role in the pathogenesis, namely cardiovascular disease and cancer. Consequently, the general aim was to study the association between oral biofilm and certain oral micro-organisms, periodontal disease, and selected inflammatory markers with a focus on atherosclerosis and breast cancer (BC). READ MORE