Search for dissertations about: "high-throughput solid phase extraction"

Showing result 1 - 5 of 8 swedish dissertations containing the words high-throughput solid phase extraction.

  2. 1. High-throughput screening of solid-phase extraction materials using mass spectrometry

    Author : Kishore Jagadeesan; Avdelningen för Biomedicinsk teknik; []
    Keywords : mass spectromery; protein separation; sample preparation; Molecularly imprinted polymer; Data analysis; Data visualization; Miniaturisation; Proteomics;

    Abstract : In biomarker analysis, sample preparation plays a crucial step in order to extract, isolate and concentrate the analytes of interest. Among the various sample preparation techniques, solid phase extraction (SPE) is one of the most common and popular, due to the high enrichment factor, good recovery, low consumption of organic solvents and the possibility to automate (off- or on-line) the whole process. READ MORE

  4. 2. Assessing the longitudinal trend of POP concentrations in humans using high-throughput sample preparation methods developed for low-volume samples

    Author : Jordan Stubleski; Anna Kärrman; Samira Salihovic; Petr Kukucka; Jean-Francois Focant; Örebro universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Longitudinal trends; human biomonitoring; POPs; PFASs; high-throughput solid phase extraction; high-resolution mass spectrometry; tandem mass spectrometry;

    Abstract : Human exposure to anthropogenic persistent organic pollutants (POPs) and their related effects on human health widely vary from person to person, making population-based risk assessment difficult.This thesis aimed to evaluate how individual changes and implemented re-strictions in POP production influenced human exposure. READ MORE

  5. 3. Towards more selective sorbents for extraction of drugs and biomarkers from biological fluids using molecularly imprinted polymers

    Author : Mohammad Mahdi Moein; Mohamed Abdel-Rehim; Milton L. Lee; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; molecularly imprinted polymer; sol-gel; solid phase extraction; microextraction by packed sorbent; monolithic column; Analytical Chemistry; analytisk kemi;

    Abstract : Sample preparation has a critical role as a first step in analytical processes, especially in bioanalysis and environmental analysis. A good sample preparation technique should be robust and stable, regardless of the sample matrix. READ MORE

  6. 4. Biomarker detection via lab-on-a-chip integrated immunoaffinity approach for fluorescence and mass spectrometry readout

    Author : Asilah Ahmad Tajudin; Avdelningen för Biomedicinsk teknik; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; immunoaffinity; affinity prefractionation; immunoMALDI; solid-phase extraction; protein digestion; ISET; antibody microarray; signal amplification; fluorescence; microfluidics; lab on a chip; separation; acoustophoresis; ultrasound; acoustic radiation force; plasma; proteomics; MALDI mass spectrometry; immunoassay; porous silicon.;

    Abstract : The blood/plasma protein biomarker profile represents the pathological and physiological changes relating to human diseases. However, the plasma proteome reflects a high degree of complexity that results in a challenge for most analytical methods in clinical diagnostics. READ MORE

  7. 5. New Techniques for Sample Preparation in Analytical Chemistry

    Author : Zeki Altun; Karlstads universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chemistry; Kemi; Kemi; Chemistry;

    Abstract : Sample preparation is often a bottleneck in systems for chemical analysis. The aim of this work was to investigate and develop new techniques to address some of the shortcomings of current sample preparation methods. READ MORE