Search for dissertations about: "highly malignant lymphoma"

Showing result 6 - 10 of 21 swedish dissertations containing the words highly malignant lymphoma.

  2. 6. Tumor-targeted superantigens for experimental immunotherapy of human leukemia/lymphoma

    Author : Cecilia Weigelt; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; SAg; SEA; SEAm; HLA class II; TCR; CFL; SDCC; cytotoxicity; TNF a; IFN g; mAb; PA-SEAm; anti-CD19-Fab-SEAm; B-CLL; B-NHL; AML; CML; immunotherapy; Onkologi; Oncology; Onkologi; Clinical Immunology; klinisk immunologi;

    Abstract : Bacterial superantigens (SAgs) have the property of stimulating high proportions of T cells expressing certain TCR Vβ sequences. The SAg first binds with high affinity to HLA class II molecules on the target cell and then stimulates the T cell to produce cytokines and to become cytotoxic. READ MORE

  4. 7. In silico analysis of pathways targeted by EBV infection and malignant transformation

    Author : Ramakrishna Rao Sompallae; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Bioinformatics; systems biology; gene expression analysis; Epstein-Barr virus; Burkitt s lymphoma;

    Abstract : Epstein-Barr virus (EBV) is a ubiquitous γ-herpes virus with dual cell tropism for human B-lymphocytes and epithelial cells. EBV infection is linked to several malignancies such as Burkitt s lymphoma (BL) and nasopharyngeal carcinoma (NPC). READ MORE

  5. 8. Genetic characterization of hematological malignancies with focus on mantle cell lymphoma

    Author : Emma Flordal Thelander; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Lymphoid cancer affects about 2000 individuals in Sweden every year. Lymphoma is divided into numerous subclasses based on histopathological and phenotypic characterization, however, for some lymphoma entities, the classification criteria are insufficient and clinical diversity is seen in cases of the same diagnosis. READ MORE

  6. 9. Studies on the regulation and function of lipoxygenases in Hodgkin lymphoma

    Author : Hongya Han; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Hodgkin lymphoma (HL) is a unique entity among the lymphomas, with a minority of malignant Hodgkin and Reed-Sternberg (H-RS) cells surrounded by a broad range of infiltrating cells. The infiltration of certain inflammatory cells has been reported to predict prognosis of the disease. READ MORE

  7. 10. Characterization of the genome and tumor microenvironment of human B-cell lymphoma

    Author : Xiaofei Ye; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Non-Hodgkin lymphoma (NHL) is the 13th most common type of cancer worldwide in 2020 and consists mainly of human B-cell lymphoma (approximately 85%). Diffuse large B-cell lymphoma (DLBCL) is the most common NHL subtype (approximately 30%). READ MORE