Search for dissertations about: "histone acetylation"

Showing result 16 - 20 of 62 swedish dissertations containing the words histone acetylation.

  2. 16. On histone deacetylases in the epigenetic regulation of neural stem and cancer cell fate

    Author : Karolina Wallenborg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Development of an organism requires correct spatial and temporal regulation of gene expression. Epigenetic regulation of gene expression has been shown to be an important part of many cellular events. Nucleosomes consist of two subunits of each core histone proteins H2A, H2B, H3, H4, and 146 base pairs of DNA, wrapped around the histones. READ MORE

  4. 17. Regulation of differentiation during the Giardia life cycle : An insight into the molecular control

    Author : Laura Rojas-López; Staffan Svärd; Marco Lalle; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Giardia; cell differentiation; encystation; histone post-translational modifications; host-parasite interaction;

    Abstract : Giardia intestinalis (syn. G. lamblia, G. duodenalis) is an intestinal protozoan parasite that causes diarrheal infections worldwide. READ MORE

  5. 18. Gene regulation mechanisms by the transcriptional coregulator mastermind-like 1

    Author : Mariana Saint Just Ribeiro; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Acetylation autoacetylation; chromatin; trnascription; coregulator; Mastermind-like 1 MAML1 ; p300; Notch signaling; phosphorylation; GSK3beta;

    Abstract : MAML1 was first identified as a coactivator for Notch receptors, but later it was also found to function as a coactivator for several other activators, including p53, beta-catenin, and MEF2C. MAML1 is critical for Notch signalling and has been shown to act cooperatively with the histone acetyltransferase (HAT) p300 in transcription that is mediated by the Notch intracellular domain (Notch IC). READ MORE

  6. 19. The CHD chromatin remodeling factors in schizosaccharomyces pombe

    Author : Julian Walfridsson; Karl Ekwall; Pernilla Bjerling; Stefan Björklund; Södertörns högskola; Karolinska Institutet; Karolinska Institutet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Regulation of chromatin structure is essential in a wide variety of processes including transcriptional regulation, recombination, replication, chromosome segregation, development and differentiation. The enzymes that are central in regulating chromatin structure can be classified into two major groups. READ MORE

  7. 20. Transcription regulation across levels of chromatin organization

    Author : Roshan Vaid; Mattias Mannervik; Goncalo Castelo-Branco; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transcription; chromatin; epigenetics; Drosophila; embryo development; molekylär biovetenskap; Molecular Bioscience;

    Abstract : With advancements in high-throughput sequencing and high-resolution microscopy techniques, the significance of genome organization in transcription regulation is rapidly unveiling. Nonetheless, we are yet far from completely understanding this key relationship. READ MORE