Search for dissertations about: "histone ubiquitylation"

Found 3 swedish dissertations containing the words histone ubiquitylation.

2. 1. Methyltransferase Ash1, histone methylation and their impact on Polycomb repression

   Author : Eshagh Dorafshan Esfahani; Yuri B. Schwartz; Jan Larsson; Dale Dorsett; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Trithorax Group proteins; Polycomb Group proteins; PRC1; PRC2; PRE; histone methylation; histone ubiquitylation; Ash1; SET domain; H3K36; H3K27; Drosophila;

   Abstract : Antagonistic interactions between Polycomb Group (PcG) and Trithorax Group (TrxG) proteins orchestrate the expression of key developmental genes. Distinct maternally loaded repressors establish the silenced state of these genes in cells where they should not be expressed and later PcG proteins sense whether a target gene is inactive and maintain the repression throughout multiple cell divisions. READ MORE

4. 2. Unwrapping the role of WRAP53β in DNA damage response

   Author : Hanif Rassoolzadeh; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : WRAP53β is a WD40 domain protein with multifaceted capabilities in several biological processes in different cellular compartments. This includes transportation of the Survival of motor neuron (SMN) complex, small Cajal body-specific (sca) RNAs and the telomerase enzyme to Cajal bodies, as well as targeting of the E3 ligase RNF8 to DNA double-strand breaks (DSBs). READ MORE

5. 3. Interplay between the Myc oncoprotein, cyclin-dependent kinases and E3 ubiquitin ligases

   Author : Hamid Reza Sharifi; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Mammalian cells grow, divide, and die in a precise and orderly fashion. For cells to grow and maintain their integrity they need to communicate at both intracellular and extracellular level. READ MORE