Search for dissertations about: "hiv-1 reverse transcriptase"
Showing result 6 - 10 of 49 swedish dissertations containing the words hiv-1 reverse transcriptase.
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6. Structure-aided design of antiviral drugs : Application of the method on HIV-1 protease and SIV reverse transcriptase
Abstract : Many efforts have been made to control the AIDS epidemic. Extensive studies have been done on the biology, biochemistry, and structural biology of HIV in the search for antiviral drugs. The viral-encoded enzymes reverse transcriptase and protease have been main targets for drug design. READ MORE
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7. Inferring transmission dynamics from HIV-1 genealogies
Abstract : With a national prevalence of 4.9% in the adult population, the HIV-1 epidemic in Kenya is the fifth largest in the world. READ MORE
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8. From Physicochemical Features to Interdependency Networks : A Monte Carlo Approach to Modeling HIV-1 Resistome and Post-translational Modifications
Abstract : The availability of new technologies supplied life scientists with large amounts of experimental data. The data sets are large not only in terms of the number of observations, but also in terms of the number of recorded features. READ MORE
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9. Cyclic Sulfamide HIV-1 Protease Inhibitors : Design, Synthesis and Modelling
Abstract : Ten years ago, the first protease inhibitor targeting the human immunodeficiency virus (HIV) was approved for clinical use. Highly active antiretroviral therapy (HAART), which combined protease and reverse transcriptase inhibitors, quickly became the standard therapy for treating patients infected with HIV and Acquired Immune Deficiency Syndrome (AIDS). READ MORE
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10. Targeting HIV-1 entry and reverse transcription by vaccination
Abstract : Human immunodeficiency virus type I (HIV-1) is a complex retrovirus, which uses the CD4 receptor and chemokine receptors to infect its target cells. The chemokine receptor CCR5 is essential for primary HIV-1 infection. The hallmark of retroviruses is the enzyme reverse transcriptase (RT), which transcribes the virus genome from RNA to DNA. READ MORE