Search for dissertations about: "hjärt- och kärlforskning"

Showing result 1 - 5 of 12 swedish dissertations containing the words hjärt- och kärlforskning.

  1. 1. Fibrinolytic factors in relation to anthropometry and incident type 2 diabetes

    Author : Jenny Hernestål Boman; Lars Johansson; Jan-Håkan Jansson; Tomas Lindahl; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; folkhälsa; Public health; cardiovascular disease; hjärt- och kärlforskning;

    Abstract : Fibrinolytic imbalance is associated with cardiovascular disease and its risk factors. The longitudinal changes in the fibrinolytic factors tissue plasminogen activator (tPA), plasminogen activator inhibitor-1 (PAI-1) and tPA/PAI-1 complex have been inadequately studied in the general population and in relation to incident type 2 diabetes mellitus (T2DM). READ MORE

  2. 2. Endogenous and exogenous factors affecting lipoprotein lipase activity

    Author : Mikael Larsson; Gunilla Olivecrona; Aivar Lookene; Ira Tabas; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LPL; APOC1; APOC2; APOC3; ANGPTL4; enzyme inactivation; lipoprotein metabolism; triglycerides; fatty acids; hypertriglyceridemia; CVD; small molecule screening; structure-activity relationship; cardiovascular disease; hjärt- och kärlforskning;

    Abstract : Individuals with high levels of plasma triglycerides are at high risk to develop cardiovascular disease (CVD), currently one of the major causes of death worldwide. Recent epidemiological studies show that loss-of-function mutations in the APOC3 gene lower plasma triglyceride levels and reduce the incidence of coronary artery disease. READ MORE

  3. 3. Secondary prevention after acute coronary syndrome : antiplatelet therapy and risk factor control

    Author : Robin Henriksson; Thomas Mooe; Fredrik Björklund; Stefan James; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute coronary syndrome; secondary prevention; myocardial infarction; ischemic stroke; antiplatelet therapy; risk factors; randomized controlled trial; cardiovascular disease; hjärt- och kärlforskning; kardiologi; Cardiology;

    Abstract : Background: One of the leading causes of death and disability worldwide is cardiovascular disease (CVD), including acute myocardial infarction (AMI). Despite improvements in medical treatment, management, and care over the years and the halving of mortality in recent decades, there is considerable room for improvement. READ MORE

  4. 4. Ultrasound measurements of subclinical carotid atherosclerosis : methodological and clinical studies

    Author : Emma Nyman; Christer Grönlund; Ulf Näslund; Isabel Gonçalves; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; atherosclerosis; ultrasound; carotid artery; carotid intima media thickness; carotid plaque; reproducibility; intervention; echogenicity; cardiovascular disease; hjärt- och kärlforskning;

    Abstract : Ultrasound measurements of subclinical carotid atherosclerosis have been evaluated as an additional parameter in risk evaluation of cardiovascular diseases (CVD). The overall aim of this thesis was to increase knowledge regarding ultrasound measurements of subclinical carotid atherosclerosis. READ MORE

  5. 5. Genetic studies in rheumatoid arthritis : familial studies and analysis of relationships to atherothrombotic comorbidity

    Author : Lisbeth Ärlestig; Solbritt Rantapää Dahlqvist; Dan Holmberg; Åsa Torinsson Naluai; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rheumatoid arthritis; genetics; familial studies; ACPA and cardiovascular co-morbidity; reumatologi; rheumatology; genetik; Genetics; cardiovascular disease; hjärt- och kärlforskning;

    Abstract : Background. Rheumatoid arthritis (RA) is an autoimmune disease mainly affecting the joints but has also extra articular manifestations and an increased cardiovascular (CV) co-morbidity. Rheumatoid factor (RF) and antibodies against citrullinated proteins/peptides (ACPA) are diagnostically important and are related to a more severe disease. READ MORE