Search for dissertations about: "hnRNP"

Showing result 1 - 5 of 29 swedish dissertations containing the word hnRNP.

  2. 1. The role of hnRNP A1 and hnRNP C1/C2 in the regulation of the stress responsive genes Cyp2a5/2A6 and p53

    Author : Kyle Christian; Matti Lang; Françoise Raffalli-Mathieu; Kirsi Vähägangas; Uppsala universitet; []
    Keywords : Molecular biology; hnRNP; Tumor Suppressor Protein p53; CYP2A5; CYP2A6; Apoptosis; hnRNP C Proteins; hnRNP protein A1; Cancer; Molekylärbiologi;

    Abstract : The family of proteins known as heterogeneous nuclear ribonucleoproteins (hnRNPs) is large and diverse. Often, one and the same hnRNP will perform multiple cellular functions, leading to their description as “multifunctional proteins”. READ MORE

  4. 2. Regulation of human papillomavirus 16 gene expression at the level of mRNA processing

    Author : Chengyu Hao; Avdelningen för medicinsk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HPV16; Alternative Splicing; hnRNPs; SR proteins; hnRNP D; hnRNP G; E6; E7 and E2;

    Abstract : .... READ MORE

  5. 3. The Multifunctional HnRNP A1 Protein in the Regulation of the Cyp2a5 Gene : Connecting Transcriptional and Posttranscriptional Processes

    Author : Tina Glisovic; Matti Lang; Francoise Raffalli-Mathieu; Lorenz Poellinger; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biochemistry; Cyp2a5; DNA-protein interaction; gene regulation; hnRNP A1; nucleocytoplasmic shuttling; RNA-protein interaction; RNA stabilization; posttranscriptional; transcriptional; Farmaceutisk biokemi; Pharmaceutical biochemistry; Farmaceutisk biokemi;

    Abstract : The mouse xenobiotic-inducible Cyp2a5 gene is both transcriptionally and posttranscriptionally regulated. One of the most potent Cyp2a5 inducers, the hepatotoxin pyrazole, increases the CYP2A5 mRNA half-life. READ MORE

  6. 4. Regulation of Human Papillomavirus Type 16 Late L1 mRNA Splicing

    Author : Xiaoze Li; Avdelningen för medicinsk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HPV-16; cervical cancer; RNA processing; alternative splicing; splicing enhancer; splicing silencer; viral persistance; SR proteins; hnRNP proteins;

    Abstract : Human papillomaviruses (HPVs) cause almost half of the human cancers that are attributable to viruses. HPV type 16 is the most carcinogenic type among the HPVs and is detected in 50% of all cervical cancers. HPV-16 infects epithelial cells and HPV-16 gene expression is tightly linked to the differentiation stage of the infected cells. READ MORE

  7. 5. The Role of Polyadenylation in Human Papillomavirus Type 16 Late Gene Expression

    Author : Daniel Öberg; Stefan Schwartz; Sheila Graham; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; HPV-16; polyadenylation; mRNA stability; codon usage; hnRNP H; DSE; splicing; negative element; RNA processing; Molekylärbiologi; Molecular biology; Molekylärbiologi;

    Abstract : High-risk type human papillomaviruses (HPVs) are associated with cancer. HPVs are strictly epitheliotropic and infect basal cell layers, establishing a life cycle strongly linked to the differentiation stage of the infected cells. The viral capsid late genes, L2 and L1, are only expressed in terminally differentiated epithelium. READ MORE