Search for dissertations about: "holm collagen"

Found 3 swedish dissertations containing the words holm collagen.

2. 1. The MHC-glycopeptide-T cell interaction in collagen induced arthritis : a study using glycopeptides, isosteres and statistical molecular design in a mouse model for rheumatoid arthritis

   Author : Lotta Holm; Jan Kihlberg; Morten Grötli; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Rheumatoid arthritis; collagen; T-cell; class II MHC; solid phase peptide synthesis; glycopeptide; peptide isostere; PCA; statistical molecular design; PLS; QSAR; sequence binding motif; Organic chemistry; Organisk kemi;

   Abstract : Rheumatoid arthritis (RA) is an autoimmune disease affecting approximately 1% of the population in the western world. It is characterised by a tissue specific attack of cartilage in peripheral joints. Collagen induced arthritis (CIA) is one of the most commonly used animal models for (RA), with similar symptoms and histopathology. READ MORE

4. 2. Glycopeptides from Type II Collagen in a Model for Rheumatoid Arthritis

   Author : Björn Holm; Umeå universitet; []
   Keywords : ;

   Abstract : .... READ MORE

5. 3. Ocean chemistry and the evolution of multicellularity

   Author : Emma U. Hammarlund; Stefan Bengtson; Donald Canfield; Nils Holm; Graham Budd; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Geochemistry; biology; paleontology; evolution; multicellularity; geokemi; Geochemistry;

   Abstract : Oxygen has been assumed to be a vital trigger for the evolution of multicellular life forms on Earth, partly based on its power to promote substantial energy flux in cell respiration and partly as biosynthesis of compounds like collagen require oxygen. However, the co-evolution of large life and the Earth’s chemical environment is not well understood at present, and there is particular disagreement in the field about whether the Cambrian explosion of animal life forms was a chemical or biological event. READ MORE