Search for dissertations about: "homologous recombination"

Showing result 11 - 15 of 90 swedish dissertations containing the words homologous recombination.

  2. 11. Helicobacter pylori : molecular mechanisms for variable adherence properties

    Author : Anna Vallström; Anna Arnqvist; Kristian Riesbeck; Umeå universitet; []
    Keywords : H. pylori; adherence; BabA; SabA; Leb; sLex; phase variation; recombination; vesicles;

    Abstract : More than half of all people worldwide are infected with H. pylori. The infection always cause a gastric inflammation that may develop into peptic ulcer disease or gastric cancer. Attachment proteins, adhesins, mediate specific adherence of H. READ MORE

  4. 12. Evolution of human alpha-herpesviruses

    Author : Peter Norberg; Göteborgs universitet; []
    Keywords : HSV-1; HSV-2; VZV; evolution; recombination; phylogenetic analysis;

    Abstract : Herpesviridae is a large virus family with more than 100 members, which are highly disseminated among animals. Three sub-families have been classified; alpha-herpesviruses, beta-herpesviruses and gamma-herpesviruses. READ MORE

  5. 13. Structural Adaptation of DNA to Small Ligands and Recombination Proteins

    Author : Hye-Kyung Kim; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; triplex DNA; groove binders; intercalators; SANS; DNA; optical spectroscopy; recombination proteins;

    Abstract : In order to contribute to the understanding of mechanisms of recognition in nucleic acid systems, the interaction of DNA with a variety of ligands, representing different cases of adaptation of the double-helix structure, was studied using flow linear dichroism (LD), circular dichroism (CD), fluorescence and absorption spectroscopic techniques. A chiral hydrophobic metal complex, [Ru(dpphen)3]2+ was examined, since this had been reported to be the most efficient molecule to discriminate DNA handedness. READ MORE

  6. 14. Replication Dynamics in the DNA Damage Response

    Author : Petra Groth; Thomas Helleday; Geroge Iliakis; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; DNA damage; DNA replication; homologous recombination; DNA double strand-breaks; ionizing radiation; alkylating agents; NATURAL SCIENCES; NATURVETENSKAP; Genetics; Genetik; molekylärgenetik; Molecular Genetics;

    Abstract : Faithful DNA replication is essential and the induction of replication stress may have profound effects on genomic integrity. This is demonstrated by the formation of DNA double strand breaks (DSBs), considered to be the most toxic DNA lesions, at stalled replication forks. READ MORE

  7. 15. Endonuclease II - a GIY-YIG enzyme of bacteriophage T4

    Author : Pernilla Lagerbäck; Karin Carlson; Elisabeth Raleigh; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; GIY-YIG; EndoII; endonuclease; structure; tetramer; binding; nicking; recombination; Microbiology; Mikrobiologi;

    Abstract : Endonuclease II (EndoII) of bacteriophage T4 is a GIY-YIG enzyme involved in host DNA breakdown during phage infection of E. coli. EndoII combines features of restriction endonucleases with those of homing endonucleases in that it breaks down DNA foreign to itself but recognizes a 16 bp long asymmetric and ambiguous sequence. READ MORE