Search for dissertations about: "horizontal gene transfer"

Showing result 6 - 10 of 60 swedish dissertations containing the words horizontal gene transfer.

  2. 6. Hidden Diversity Revealed : Genomic, Transcriptomic and Functional Studies of Diplomonads

    Author : Jon Jerlström-Hultqvist; Staffan Svärd; Adrian Hehl; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Giardia intestinalis; Spironucleus salmonicida; Spironucleus barkhanus; intestinal parasite; hydrogenosome; mitosome; lateral gene transfer; horizontal gene transfer; diplomonad; metamonad; sexual recombination; transfection; protein complex purification; Biology with specialization in Evolutionary Organismal Biology; Biologi med inriktning mot evolutionär organismbiologi; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Biologi med inriktning mot molekylär evolution; Biology with specialization in Molecular Evolution;

    Abstract : The diplomonads are a diverse group of eukaryotic microbes found in oxygen limited environments such as the intestine of animals were they may cause severe disease. Among them, the prominent human parasite Giardia intestinalis non-invasively colonizes the small intestine of humans and animals where it induces the gastrointestinal disease giardiasis. READ MORE

  4. 7. Advancing systems biology of yeast through machine learning and comparative genomics

    Author : Le Yuan; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; enzyme turnover number; gene essentiality; horizontal gene transfer; machine learning; deep learning; yeast species;

    Abstract : Synthetic biology has played a pivotal role in accomplishing the production of high value commodities, pharmaceuticals, and bulk chemicals. Fueled by the breakthrough of synthetic biology and metabolic engineering, Saccharomyces cerevisiae and various other yeasts (such as Yarrowia lipolytica , Pichia pastoris ) have been proven to be promising microbial cell factories and are frequently used in scientific studies. READ MORE

  5. 8. Homing Endonucleases and Horizontal Gene Transfer in Bacteria and Bacteriophages

    Author : David Nord; Britt-Marie Sjöberg; Steinar Johansen; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; dsDNA cleavage; ribonucleotide reductase; GIY-YIG motif; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Abstract : Homing endonuclease genes (HEGs) are selfish genetic elements that mediate their own super-Mendelian inheritance. This is mediated by the homing endonuclease cleavage of a HEG- allele followed by recombination-repair with a HEG+ allele.The majority of the HEGs are encoded in intervening sequences (IVSs). READ MORE

  6. 9. Inferring evolution in bacteria using Markov chains and genomic signatures

    Author : Daniel Dalevi; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Prediction suffix tree; Markov chains; Molecular evolution; Bioinformatics; Gene order rearrangements; Horizontal gene transfer; Variable length Markov chains;

    Abstract : This thesis concerns the development of methods and models in evolutionary molecular biology. The techniques are also applicable to other similar biological problems. The first contribution is a novel classifier using fixed and variable length Markov chains that can discriminate between bacterial DNA of different species. READ MORE

  7. 10. Antibiotic sensitivity and horizontal gene transfer in Escherichia coli - A genome-wide perspective

    Author : Martin Palm; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; antibiotics; antibiotic resistance; Escherichia coli; heavy metals; bacterial conjugation; pangenome; sub-inhibitory;

    Abstract : Since their discovery in the early 20th century, antibiotics have truly revolutionized human medicine. They have allowed us to treat diseases that were previously untreatable and have become a staple of modern medicine. However, along with the human use of antibiotics pathogens resistant to antibiotics emerged. READ MORE