Search for dissertations about: "hormone analysis"

Showing result 1 - 5 of 282 swedish dissertations containing the words hormone analysis.

2. 1. Prediction Models and Pharmacogenomics in Adult Growth Hormone Deficiency

   Author : Edna J L Barbosa; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; growth hormone deficiency; hypopituitarism; growth hormone replacement therapy; prediction models; candidate gene approach; polymorphisms; body composition; growth hormone receptor; lipid metabolism; extracellular water; pharmacogenomics;

   Abstract : The overall aim of this thesis was to study clinical and genetic factors that influence response to growth hormone replacement therapy (GHRT) in GH deficient (GHD) adults. The patients were part of a cohort of adults with hypopituitarism and severe GHD who were studied before and after 12 months of GHRT. READ MORE

4. 2. Quality of Life in Adult Patients with Growth Hormone Deficiency : Bridging the gap between clinical evaluation and health economic assessment

   Author : Maria Kołtowska-Häggström; Kesrtin (Chris) Bingefors; Dag Isacson; Paul Kind; Jens Sandahl Christiansen; Uppsala universitet; []
   Keywords : Health policy and health economics; growth hormone deficiency in adults; quality of life; cost-utility analysis; growth hormone replacement; normative data; QoL-AGHDA; Hälsopolitik och hälsoekonomi;

   Abstract : The goals of this thesis are to evaluate quality of life (QoL) in adult patients with growth hormone deficiency (GHD) in relation to population normative data, to construct a preference-weighted index (utility) from a disease-specific QoL measure and to assess it in a clinical context.The study included samples from the general population and patients with GHD from four European populations: England & Wales, the Netherlands, Spain and Sweden. READ MORE

5. 3. Testosterone Analysis in Hair

   Author : Julia Preinbergs; Jakob Ström; Elvar Theodorsson; Edvin Ingberg; Ulrik Kvist; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : The effects of testosterone in the body are dependent on the concentrations at the target organs, as well as the susceptibility of the androgen receptor. Steroid hormones circulate in the bloodstream bound to proteins, and only a small part is unbound and free to exert its effect at the receptors. READ MORE

6. 4. Integrative Approaches in Shotgun Proteomics : From sample preparation to multifaceted data analysis

   Author : Mariya Nezhyva; Erik T. Jansson; Per Andrén; Gustaf Christoffersson; Jesper Velgaard Olsen; Uppsala universitet; []
   Keywords : bottom-up proteomics; thermal proteome profiling; mass-spectrometry imaging; data analysis; melanocortin receptor; Farmaceutisk vetenskap; Pharmaceutical Science;

   Abstract : Bottom-up proteomics mass-spectrometry gives an opportunity to shed light on var-ious biological aspects/characteristics such as protein composition, its modifications,interactions, and dynamics. Its applications span a wide range of biological sciencesaiming to eventually answer fundamental disease related questions or evaluate drugperformance and predict adverse effects. READ MORE

7. 5. Endocrine markers of ovarian function: Clinical and biological aspects with focus on Anti Müllerian hormone

   Author : Leif Bungum; Malmö Reproduktionsmedicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anti Müllerian Hormone; ovarian reserve; biomarker; Luteinizing Hormone; fecundity; fertility; Time to Pregnancy;

   Abstract : Declining birthrates and infertility are now a common problem in the Western World. Due to the tendency to postpone childbearing an increasing age of women who consider motherhood is generally seen. READ MORE