Search for dissertations about: "hormone replacement therapy HRT"

Showing result 11 - 15 of 32 swedish dissertations containing the words hormone replacement therapy HRT.

2. 11. Essays on economic evaluation in health care : evaluation of hormone replacement therapy and uncertainty in economic evaluations

   Author : Niklas Zethraeus; Handelshögskolan i Stockholm; []
   Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES;

   Abstract : This thesis contains six papers closely related to current research topics in the field of economic evaluation in health care. The thesis discusses methodological features of cost-effectiveness analysis (CEA) and cost-benefit analysis (CBA). It further relates to issues of modelling and how to account for uncertainty in economic evaluations. READ MORE

4. 12. Endothelium-derived Vasoactive Factors and Leukocyte-derived Inflammatory Mediators. Studies in subjects with or at risk for vascular disease

   Author : Anwaar M Ibrahim; Malmö Institutionen för kliniska vetenskaper; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostacyclin.; Postmenopausal hormone replacement therapy; Nitric oxide; Endothelin; Diabetes mellitus; Cytokines; Cholesterol; Atherosclerosis; Cerebral ischemia; Cardiovascular system; Kardiovaskulära systemet;

   Abstract : This study was undertaken to evaluate relationships between endothelial function (assessed as mediators of endothelium-derived vasoactive factors such as nitric oxide [NO], prostacyclin [PGI2] and endothelin [ET-1] ), and risk factors for atherosclerosis, as well as to study possible relationships between endothelial function and leukocyte activation (indicated by measurements of leukocyte-derived inflammatory mediators) in subjects with or at risk for atherosclerosis. In subjects with asymptomatic atherosclerosis we found inverse relationships between cyclic guanosine monophosphate (cGMP) in platelets (mediator of NO activity) and both serum total cholesterol and plasma ET-1 suggesting that NO-mediated vasodilation may be impaired in hypercholesterolemia and that maintenance of vascular tone is achieved by a balance between NO and ET-1. READ MORE

5. 13. An epidemiologic study of epithelial ovarian malignancies : with a focus on hormone-related factors

   Author : Tomas Riman; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Epithelial ovarian cancer; borderline ovarian tumors; epidemiology; risk factors; reproductive history; oral contraceptives; hormone replacement therapy; estrogens; progestins; case-control studies.;

   Abstract : The main purpose of this thesis was to examine estrogen and progestin effects of hormone replacement therapy, in relation to the risk for epithelial ovarian neoplasias. Other intentions were to assess reproductive factors, oral contraceptive use, previous gynecologic surgeries, and family history of ovarian cancer according to the risk of ovarian neoplasias, and to connect these findings to different hypotheses regarding ovarian carcinogenesis. READ MORE

6. 14. Hormonal treatments and the breast : effects on sex steroid receptor expression and proliferation

   Author : Erika Isaksson Friman; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Oral contraceptives; hormone replacement therapy; breast epithelial proliferation; cynomolgus macaques; ER-alpha and ER-beta; PRA and PRB; tamoxifen; IGF-I; p53.;

   Abstract : Breast cancer is the most common malignancy among women in the western world. Hormonal treatments for contraception and replacement after menopause have been associated with an increased risk of breast cancer. The basis of risk associated with hormonal therapies may lie in the regulation of cell proliferation. READ MORE

7. 15. Breast cancer survivors : information needs, attitudes towards illness and quality of life

   Author : Birgitta Wallberg; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Breast cancer; meaning of illness; information needs; clinical trials; HRT; HRQoL;

   Abstract : Breast cancer (BC) is the most common female cancer. Only in Sweden about 7300 women are affected each year and 1500 die from the disease. Following progress in early detection and therapy there has been a marked improvement in survival and an increase in the number of BC survivors. READ MORE