Search for dissertations about: "hormone therapy"

Showing result 6 - 10 of 219 swedish dissertations containing the words hormone therapy.

2. 6. TARP Promoter-Based Prostate Cancer Gene Therapy : From Development to Application

   Author : Wing-Shing Cheng; Magnus Essand; Thomas H. Tötterman; Cecilia Lundberg; Uppsala universitet; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Genetic engineering; TARP; PPT; TSTA; promoter; gene regulation; prostate specificity; hormone- independent; adenovirus; prostate cancer; gene therapy; conditionally replicating adenovirus; Genteknik; Genetic engineering including functional genomics; Genteknik inkl. funktionsgenomik;

   Abstract : Prostate cancer is one leading cause of cancer-related death among men in Western countries. The standard therapies for localized prostate cancer include radical prostatectomy and radiation therapy. Such measures are relatively effective in the short term, but many patients ultimately relapse. READ MORE

4. 7. Life Style, Molecular Pathology, and Breast Cancer Risk

   Author : Signe Borgquist; Malmö Handkirurgi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hormone receptors; Breast cancer; tissue microarray; histopathology; ERβ; tumour proliferation; cyclin D1; p27; HMG-CoA reductas; life style factors; diet; hormone replacement therapy; obesity; endocrine therapy;

   Abstract : The breast cancer diagnosis covers a wide range of tumours with different geno- and phenotypic characteristics. The diversity among studies on life-style factors and their impact on breast cancer risk might be clarified by recognizing breast cancer as a heterogeneous disease. READ MORE

5. 8. Postmenopausal hormone therapy and cardiovascular risk

   Author : Germán D Carrasquilla; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Introduction and aims: Postmenopausal hormone therapy (HT) is the most effective treatment for menopausal symptoms, but its safety has been debated during the past 15 years. Previous observational studies showed benefits from HT, whereas subsequent large randomized clinical trials showed an increased risk for cardiovascular disease (CVD) and other chronic diseases; the pivotal difference between these studies was the average age at HT initiation. READ MORE

6. 9. Long-term effects of growth hormone replacement therapy in growth hormone deficient adults

   Author : Galina Götherström; Göteborgs universitet; []
   Keywords : growth hormone; body composition; bone mass; bone density; muscle strength; lipids; glucose metabolism; adult onset GHD; childhood onset GHD; gender;

   Abstract : Deficiency of growth hormone (GHD) in adults results in abnormal body composition, reduced bone mass and muscle strength, deteriorated cardiovascular risk factors. Short-term GH replacement reverses many of the symptoms associated with adult GHD. READ MORE

7. 10. Mammographic breast density and postmenopausal hormone therapy

   Author : Eva Lundström; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Mammographic breast density; mammography; menopause; hormone therapy; tibolone; low dose intrauterine progestogen; Syndecan-1.;

   Abstract : Breast cancer is the most frequent malignancy among women in the western world. More than one million women are estimated to be diagnosed with the disease every year. The breast is a target organ for sex steroids and hormonal treatments have been found to increase the risk for breast cancer. READ MORE