Search for dissertations about: "hormone-sensitive lipase"

Showing result 6 - 10 of 24 swedish dissertations containing the words hormone-sensitive lipase.

  2. 6. Hormone-Sensitive Lipase and Protein Kinase B; Molecular characterization in testis, adipose tissue and pancreatic beta cells

    Author : Lena Stenson; Signaltransduktionsforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; signal transduction; pancreas; beta cells; adipocyte; insulin; Akt; protein kinase B; spermatogenesis; cholesterol esterase; hormone-sensitive lipase; testis; cAMP; Proteins; enzymology; Proteiner; enzymologi;

    Abstract : Hormone-sensitive lipase (HSL) and protein kinase B (PKB) are enzymes that in different ways are associated with lipid metabolism. While HSL is the well-known lipolytic enzyme responsible for hydrolysis of stored triacylglycerols in adipose tissue, PKB is a recently identified serine/threonine protein kinase, ubiquitously expressed and involved in signal transduction pathways induced by insulin and growth factors. READ MORE

  4. 7. Hormone-Sensitive Lipase - New roles in adipose tissue biology

    Author : Kristoffer Ström; Molekylär endokrinologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; retinoid; adipogenesis; adipocyte determination; HSL; WAT;

    Abstract : Obesity is defined as abnormal or excessive fat accumulation that may impair health, and increased knowledge about the enzymes controlling lipid metabolism is of great importance in order to combat this disease. Hormone-sensitive lipase (HSL) is a key enzyme in the mobilization of fatty acids from acylglycerols in adipocytes, but also plays important roles in other cell types. READ MORE

  5. 8. Hormone-sensitive lipase: Molecular analyses of the human gene; structural and evolutionary aspects on expression, alternative splicing and cold adaptation

    Author : Henrik Laurell; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; enzymologi; Proteiner; Proteins; enzymology;

    Abstract : Hormone-sensitive lipase (HSL) is a key enzyme in adipose tissue that hydrolyses stored fat (triacylglycerol). The activity of HSL is under strict hormonal and neural control. READ MORE

  6. 9. Studies on catecholamine function in human fat cells

    Author : Lena Hellström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Adipose tissue; human; catecholamines; lipolysis; adrenoceptors; mRNAhormone-sensitive lipase; hypo-caloric diet; thyroid hormones.;

    Abstract : Human adipose tissue is a heterogeneous organ as regards metabolism. The effects of catecholamines, the main lipolytic hormones in man vary considerably in different regions. Fat cell lipolysis also changes in a number of physiological and pathophysiological states. READ MORE

  7. 10. Genetics of type 2 diabetes and the metabolic syndrome

    Author : Mia Klannemark; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetology; secreting systems; Endocrinology; PDE3B; PPARG; LPL; metabolic syndrome; diabetes; genetic; HSL; UCP2; Endokrinologi; sekretion; diabetologi;

    Abstract : Type 2 diabetes and the metabolic syndrome are highly prevalent disorders with severe complications such as cardiovascular disease. The aetiology of type 2 diabetes and the metabolic syndrome is not known, but the interaction between genetic factors and environmental triggers is important. READ MORE