Search for dissertations about: "host defence"

Showing result 16 - 20 of 132 swedish dissertations containing the words host defence.

  2. 16. Helicobacter pylori interference with the L-arginine/NO pathway in the upper gut

    Author : Charlotte Von Bothmer; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; acid; bicarbonate; duodenal ulcer; Helicobacter pylori; host defence; mucosa; nitric oxide; nitric oxide synthase;

    Abstract : Helicobacter pylori causes chronic gastritis and sometimes peptic ulcers but the pathogenesis is not fully understood. H. pylori-infected individuals with duodenal ulcer have an impaired duodenal mucosal bicarbonate secretion (DMBS) in response to acid. NO is an important signalling molecule in the body. READ MORE

  4. 17. Regulation of human cell viability by the host defence peptide LL-37

    Author : Daniel Svensson; Kärlfysiologi; []
    Keywords : LL-37; cathelicidin; cytotoxicity; host defence peptides; autoimmune diseases; inflammation; vitamin D;

    Abstract : Accumulating evidence suggests that the main human cathelicidin peptide, LL-37, may influence host cell viability and pro-inflammatory signaling when locally overexpressed. LL-37 has pro-inflammatory properties linked to the development of for example psoriasis, rosacea, SLE and atherosclerosis. READ MORE

  5. 18. Reactive oxygen and nitrogen in host defence against Francisella tularensis

    Author : Helena Lindgren; Anders Sjöstedt; Tommy Sundquist; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Francisella tularensis; inducible nitric oxide synthase; phagocyte oxidase; macrophages; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; klinisk bakteriologi; Clinical Bacteriology;

    Abstract : Francisella tularensis, the causative agent of tularemia, is a potent human and animal pathogen. Initially upon infection of the host, intramacrophage proliferation of F. tularensis occurs but after activation of the acquired host immunity, the phagocytes become activated to kill the bacterium. In my thesis, I focused on mechanisms utilized by F. READ MORE

  6. 19. The streptococcal IgG degrading enzyme IdeS : studies on host-pathogen interactions

    Author : Jenny Johansson Söderberg; Ulrich von Pawel-Rammingen; Jan Ingemar Flock; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; streptococcus pyogenes; IdeS; molekylärbiologi; Molecular Biology;

    Abstract : The important human pathogen Streptococcus pyogenes causes both mild infections such as pharyngitis and impetigo but also severe life threatening invasive infections.  Specific antibodies (IgG) recognize pathogens and are important mediators for pathogen clearance by the immune defence. S. READ MORE

  7. 20. Molecular and cellular interactions on noble metal nanopatterned surfaces − applications towards bone, soft tissue and infection control

    Author : Sara Svensson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nanotopography; noble metals; titanium; biocompatibility; osseointegration; inflammation; host defence; monocytes; infection control; antimicrobial; staphylococci;

    Abstract : Biomaterial-associated infection is recognised as one of the main risks for failure of medical devices. The presence of a foreign material in tissues has been suggested to compromise the ability of host cells to eradicate infection. READ MORE