Search for dissertations about: "host-microbe interaction"

Showing result 1 - 5 of 7 swedish dissertations containing the words host-microbe interaction.

  2. 1. Antimicrobial peptides and proteins in host-microbe interaction and immediate defense

    Author : Ylva Kai-Larsen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Antimicrobial peptides and proteins (AMPs) are effector molecules of innate immunity and are capable to kill a broad spectrum of microbes, i.e. bacteria, fungi and viruses. They are widespread in nature and have been found in almost all species of the animal kingdom, as well as in plants. READ MORE

  4. 2. Metagenomic Characterization of the Gut Microbiome in Cohorts of Elderly

    Author : Sukithar K Rajan; Dirk Repsilber; Carl Mårten Lindqvist; Robert Jan Brummer; Lars-Gustav Snipen; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gut microbiota; metagenomics; High-Throughput Nucleotide Sequencing; reference sequence database; methods validation; microbial function; host-microbe interaction;

    Abstract : Human gut microbiota plays a vital role in maintaining host health. This thesis aims to investigate the gut microbial population and function using next generation sequencing (NGS) data from faecal samples. Paper I examines the influence of sequencing depth and analysis methods in microbiota profiling using NGS whole genome sequencing (WGS) data. READ MORE

  5. 3. Exploring the interaction between the human microbiota and infections

    Author : Liqin Cheng; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The microbiota is a living ecosystem that is influenced by a variety of host and environmental factors. Distinct microbiota colonizes various body sites, such as the gastrointestinal system and vaginal tract, corresponding to the unique microenvironment. A healthy gut microbiota contains a stable, balanced, and highly diverse reservoir of microbes. READ MORE

  6. 4. Effects of bacterial genotoxins on immune modulation, chronic inflammation and cancer development

    Author : Anna Bergonzini; Teresa Frisan; Maria Fällman; Steffen Backert; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunologi; Immunology;

    Abstract : The intestinal microbiome of Inflammatory Bowel Disease and colorectal cancer patients is enriched in genotoxin-producing bacteria, which cause DNA damage in the host cells.Genotoxins have recently been identified as a novel family of effectors produced by pathogenic and commensal bacteria. READ MORE

  7. 5. Urinary tract infection : pathogenesis and complications

    Author : Olof Hertting; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Urinary tract infections (UTI) are one of the most common infections in women and children worldwide. If not diagnosed and treated appropriately, it may lead to severe illness and long-term complications. The economic impact caused by UTI on society is significant. In addition, bacterial resistance to common antibiotics is spreading at a high rate. READ MORE