Search for dissertations about: "host-pathogen interactions"

Showing result 1 - 5 of 49 swedish dissertations containing the words host-pathogen interactions.

2. 1. The streptococcal IgG degrading enzyme IdeS : studies on host-pathogen interactions

   Author : Jenny Johansson Söderberg; Ulrich von Pawel-Rammingen; Jan Ingemar Flock; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; streptococcus pyogenes; IdeS; molekylärbiologi; Molecular Biology;

   Abstract : The important human pathogen Streptococcus pyogenes causes both mild infections such as pharyngitis and impetigo but also severe life threatening invasive infections.  Specific antibodies (IgG) recognize pathogens and are important mediators for pathogen clearance by the immune defence. S. READ MORE

4. 2. Diving into short linear motifs : Large-scale identification of endogenous and host-pathogen protein-protein interactions and further characterized by deep mutational scanning

   Author : Caroline Benz; Ylva Ivarsson; Birthe B. Kragelund; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein-protein interactions; short linear motif; endogenous interactions; host-pathogen; viral hijacking; deep mutational scanning; Biokemi; Biochemistry;

   Abstract : Short linear motifs (SLiMs) are protein-protein interaction sites that play an essential role in distinct cellular processes. Those interactions are challenging to capture by common high-throughput methods. READ MORE

5. 3. NMR studies of host-pathogen interactions

   Author : Katja Petzold; Jürgen Schleucher; Torleif Härd; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NMR; regulatory RNA; HBV; H.pylori; phospholipids; ROESY; Molecular biophysics; Molekylär biofysik; biokemi; Biochemistry;

   Abstract : This thesis describes the use of Nuclear Magnetic Resonance (NMR) for characterizing two host-pathogen interactions: The behavior of a regulatory RNA of the Hepatitis B virus (HBV) and the attachment of Helicobacter pylori (H. pylori) to the gastric mucosa. READ MORE

6. 4. Streptococci and Platelets - A Study of Host-Pathogen Interaction Dynamics

   Author : Lisbeth Svensson; Infektionsmedicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; host-pathogen interactions; bacterial entrapment; disaggregation; aggregation; platelet activation; Streptococci;

   Abstract : Invasive infections remains one of the leading causes of death due to infections over the world, and efficient treatment remains elusive. One of the major causes of sepsis and other invasive infections is pathogenic streptococci that cause a wide range of clinical manifestations in humans. READ MORE

7. 5. A holistic approach to host-pathogen interactions : Detecting the large to unravel the small

   Author : Kristoffer Sjöholm; Institutionen för immunteknologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mass spectromery; Proteomics; Host-pathogen interactions; Sepsis;

   Abstract : Sepsis is one of the leading causes of mortality and morbidity in the world, and is an overreaction by the immune system due to pathogen invasion of the bloodstream. The interactions, particularly the protein interactions, between the host and pathogen are fundamental for the outcome of the disease. READ MORE