Search for dissertations about: "housekeeping gene"

Showing result 1 - 5 of 19 swedish dissertations containing the words housekeeping gene.

  1. 1. Contributions to Statistical Analysis of Gene Expression Data

    University dissertation from Göteborg : Chalmers University of Technology

    Author : Anders Sjögren; Göteborgs universitet.; Gothenburg University.; [2005]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; DNA microarray; differential expression; gene regulation; variance stabilising transformation; permutation; reference gene; housekeeping gene; bootstrap; quality control QC ; quality assurance QA ; quality assessment; empirical Bayes; weighted moderated t-statistic; WAME; quality assessment; gene regulation; housekeeping gene; permutation; reference gene; variance stabilising transformation; empirical Bayes; quality control QC ; differential expression; bootstrap; weighted moderated t-statistic; quality assurance QA ; WAME;

    Abstract : .... READ MORE

  2. 2. Vector development for suicide gene therapy

    University dissertation from Stockholm : Karolinska Institutet, Department of Medicine

    Author : Alar Aints; Karolinska Institutet.; Karolinska Institutet.; [2002]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Suicide gene therapy; VP22; selection markers; Ouabain resistance gene; GvHD; retroviral gene transfer;

    Abstract : Gene therapy is used to treat conditions that arise from errors in the genetic makeup of cells either congenital diseases resulting from a deletion or mutation in a gene or malignant diseases where genetic regulation mechanisms have been deranged. Suicide gene therapy is one of several gene therapeutic approaches to treat cancer. READ MORE

  3. 3. New insights into the role of ppGpp and DksA through their effect on transcriptional regulation of housekeeping and colonization related genes of Escherichia coli

    University dissertation from Umeå : Molekylärbiologi (Medicinska fakulteten)

    Author : Anna Åberg; Carlos Balsalobre; Anne Farewell; [2008]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Escherichia coli; type 1 fimbriae; fimB; phase variation; transcription; global gene regualtion; ppGpp; DksA; gre-factors; RNA polymerase; MEDICINE Microbiology; immunology; infectious diseases Microbiology Medical microbiology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Mikrobiologi Medicinsk mikrobiologi;

    Abstract : Bacteria have the ability to sense different environmental signals. When an environmental stress is detected, bacteria rapidly adjust their gene expression profile to be able to survive and thrive. READ MORE

  4. 4. Transcriptional profiling of human embryonic stem cells and their functional derivatives

    University dissertation from Göteborg : University of Gothenburg

    Author : Jane Synnergren; Göteborgs universitet.; Gothenburg University.; [2010]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transcription; differentiation; human embryonic stem cells; gene expression;

    Abstract : Human embryonic stem cells (hESCs) represent populations of pluripotent, undifferentiated cells with unlimited replication capacity, and with the ability to differentiate into any functional cell type in the human body. Based on these properties, hESCs and their derivatives provide unique model systems for basic research on embryonic development. READ MORE

  5. 5. The effect of chronic alcoholism on epigenetic patterns regulating gene expression and neurodegeneration in the human brain

    University dissertation from Stockholm : Karolinska Institutet, Department of Clinical Neuroscience

    Author : Sofia Johansson; Karolinska Institutet.; Karolinska Institutet.; [2007]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alcoholism; cognition; drug dependence; brain; frontal cortex; motor cortex; LUMA; epigenetics; methylation; gene expression; endogenous controls; real-time PCR.;

    Abstract : Chronic alcoholism causes about 3.2% of all deaths worldwide. It has an association to about 60 different diseases and injuries with enormous social and economical impact. Despite these facts, very few pharmacological treatments exist and we can still not explain the mechanisms behind addiction, craving and cognitive impairments seen in the abuser. READ MORE