Search for dissertations about: "hsp60"

Showing result 1 - 5 of 14 swedish dissertations containing the word hsp60.

  2. 1. Studies in DNA immunization

    Author : Cecilia Svanholm; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Chlamydia pneumoniae; DNA vaccine; GM-CSF; HIV-1; hsp60; Nef; Rev; Tat; signal sequence;

    Abstract : This thesis describes investigations and developments of DNA immunization techniques, which were applied in the study of two different pathogens; HIV-1 and Chlamydia pneumoniae. DNA vaccines, i.e. naked plasmid DNA encoding an antigen, represent a novel strategy for generating protective immunity against several infectious diseases. READ MORE

  4. 2. Molecular steps towards improving prognosis in ovarian cancer

    Author : Elisabet Hjerpe; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Epithelial ovarian cancer (EOC) is the most lethal of gynecological cancers, and cure rates have improved very little in the last 30 years. The most common histological subtypes are serous, endometrioid, clear cell and mucinous EOC. To date, all EOC have been treated as one entity. READ MORE

  5. 3. Recent Developments of Chlamydia trachomatis and Mycoplasma Infections in Women

    Author : Carina Bjartling; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; uro-genital infection; Chlamydia trachomatis; Mycoplasma genitalium; pelvic inflammatory disease; cervicitis; ectopic pregnancy;

    Abstract : The aim of this thesis was to elucidate developments in epidemiology, clinical manifestations and complications in Chlamydia trachomatis (C.trachomatis) and Mycoplasma genitalium (M.genitalium) infection. READ MORE

  6. 4. Novel immunologic cellular mechanisms in atherosclerosis and potential therapeutic implications

    Author : M Mizanur Rahman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Atherosclerosis, an arterial ailment, is a major cause of cardiovascular diseases (CVD), which cause more than 17 million deaths each year and the number is expected to rise. In recent years atherosclerosis has been shown to be an inflammatory condition involving activated immunocompetent cells, including T-cells, macrophages and dendritic cells (DC), but the mechanism by which these cells are activated remains to be elucidated in detail. READ MORE

  7. 5. Sorting and Import of Plant Mitochondrial Precursor Proteins

    Author : Erik von Stednigk; David Day; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; biokemi; Biochemistry;

    Abstract : The mitochondrial genome encodes only a handful of the mitochondrial proteins; hundreds of mitochondrial proteins are encoded in the nucleus, synthesised on cytosolic polyribosomes and subsequently imported into the organelle. Most of the proteins targeted to the mitochondria are synthesised as precursors with an N-terminal extension called presequence or targeting sequence. READ MORE