Search for dissertations about: "human C4BP"
Showing result 1 - 5 of 17 swedish dissertations containing the words human C4BP.
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1. Streptococcal M protein and human C4BP
Abstract : Antigenic variation of surface proteins allows microorganisms to evade the immune system of the infected host. This phenomenon represents an apparent paradox, because the variable protein must retain an important function, while its antigenic properties vary extensively. READ MORE
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2. MORAXELLA CATARRHALIS OUTER MEMBRANE PROTEINS AND INTERACTIONS WITH THE HUMAN IMMUNE SYSTEM
Abstract : Moraxella catarrhalis is frequently colonizing the human respiratory tract, particularly in children. This gram-negative bacterium has during the last two decades been recognized as a pathogen causing otitis media in children and lower respiratory tract infections in adults with predisposing conditions such as chronic obstructive pulmonary disease (COPD). READ MORE
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3. Interactions of human C4BP with Bordetella pertussis and Streptococcus pyogenes
Abstract : Many microorganisms have developed mechanisms to protect themselves against attack from the complement system of the host. One possible mechanism for a microorganism to evade complement attack is to bind a human complement regulator, which may allow the microorganism to down-regulate complement activation. READ MORE
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4. Structural and functional studies of C4b-binding protein (C4BP)
Abstract : The subject of this thesis is complement inhibitor C4b-binding protein (C4BP), on which we have performed both structural and functional studies. Complement is part of the innate immune defence and eliminates microbes, solubilises immune complexes and is involved in the clearance of apoptotic cells. READ MORE
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5. Interactions between Streptococcus pyogenes and the human immune system, with special reference to C4b-binding protein
Abstract : The ability of many pathogenic microorganisms to cause infection is dependent on their ability to evade attack by the complement system of the host. One mechanism by which microorganisms may avoid complement attack is to bind complement inhibitory molecules present in the host. READ MORE