Search for dissertations about: "human antimicrobial peptide LL-37"

Showing result 11 - 15 of 34 swedish dissertations containing the words human antimicrobial peptide LL-37.

  2. 11. The human antimicrobial peptide hCAP18 in epithelial defense

    Author : Margareta Frohm Nilsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Innate immunity; host defense; antimicrobial peptide; hCAP 18; LL-37; epithelia; wounds; breast cancer;

    Abstract : Gene-encoded antimicrobial peptides serve a protective role in host defense. They are multifunctional effector molecules in innate immunity - the nonadaptive immune system -with the capacity to kill a broad spectrum of microorganisms. READ MORE

  4. 12. REGULATED UPTAKE OF BIOPOLYMERS Role of cell surface proteoglycans Implications for drug and gene delivery

    Author : Staffan Sandgren; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Cytology; oncology; proliferation; differentiation; Medicine human and vertebrates ; growth factor; cancer; drug delivery; gene therapy; LL-37; HIV-Tat; cell penetrating peptides; polyamines; heparan sulfate; onkologi; Cytologi; cancerology; internalization; proteoglycans;

    Abstract : Cells continuously export, import, and recycle molecules over the plasma membrane. Internalization, i.e. cellular import of extracellular material, is a fundamental process, which provides cells with nutrients and enables the immune cells of higher organisms to remove debris, sample their surroundings for antigens and to fight microbes. READ MORE

  5. 13. Studies of the role of the cathelicidin peptide LL-37 in epithelial biology

    Author : Clara Ibel Chamorro Jimenez; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The biology of epithelial immunity as well as of tissue repair is complex and highly regulated. A variety of molecules, cell types, and biological processes such as, cell differentiation, proliferation and migration, programmed cell death and antimicrobial mechanisms contribute to maintaining a balance between tissue damage and tissue repair. READ MORE

  6. 14. Studies on Staphylococcus epidermidis biofilm formation and the bacterial interaction with the human cathelicidin antimicrobial peptide LL-37

    Author : Eva Hell; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The long-term use of central venous catheters for delivering nutrients and drugs in preterm neonates has been related to nosocomial infections. The majority of late-onset sepsis in very preterm infants (... READ MORE

  7. 15. Host response in sepsis

    Author : Ingrid Berkestedt; Anestesiologi och intensivvård; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; severe sepsis; contact system; glycosaminoglycan; antimicrobial peptide; human;

    Abstract : Sepsis is a serious condition characterized by a systemic inflammatory response to an infection. Increased vascular leakage, vasodilation and heart failure cause circulatory disturbances challenging the intensivist. Despite modern medication and high technology supportive care, mortality is high. READ MORE