Search for dissertations about: "human embryo development"

Showing result 11 - 15 of 75 swedish dissertations containing the words human embryo development.

  2. 11. Glycosaminoglycan Biosynthesis in Zebrafish

    Author : Beata Filipek-Górniok; Lena Kjellén; Johan Ledin; Kay Grobe; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heparan sulfate; chondroitin dermatan sulfate; biosynthesis; development; N-deacetylase N-sulfotransferase; glycosyltransferases; morpholino; CRISPR-Cas9;

    Abstract : Proteoglycans (PGs) are composed of highly sulfated glycosaminoglycans chains (GAGs) attached to specific core proteins. They are present in extracellular matrices, on the cell surface and in storage granules of hematopoietic cells. READ MORE

  4. 12. Cannabinoids as modulators of cancer cell viability, neuronal differentiation, and embryonal development

    Author : Sofia Gustafsson; Stig Jacobsson; Birgitta Sander; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cannabinoids; cell viability; neuronal differentiation; colorectal cancer; chick embryo; biokemisk farmakologi; biochemical pharmacology; Toxicology; toxikologi;

    Abstract : Cannabinoids (CBs) are compounds that activate the CB1 and CB2 receptors. CB receptors mediate many different physiological functions, and cannabinoids have been reported to decrease tumor cell viability, proliferation, migration, as well as to modulate metastasis. READ MORE

  5. 13. The zebrafish as a model to elucidate human diseases and development

    Author : Samantha Lin Chiou Lee; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : This thesis explores the zebrafish as a model organism to illuminate our understanding of processes that orchestrate the progression of cancer metastasis and myogenesis. First, I describe the successful establishment of a cancer metastasis model in the zebrafish, specifically to study intravasation - one of the earliest steps in the metastatic cascade. READ MORE

  6. 14. Culture and vitrification of human preembryos

    Author : Fredwell Hambiliki; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Despite improvements in stimulation protocols, culture media formulations and laboratory protocols, the success rates in human IVF remain disappointingly low. The ability to successfully cryopreserve supernumerary embryos in a given IVF cycle without losing significant embryo viability is essential to maximize the cumulative benefit of a given treatment cycle. READ MORE

  7. 15. The role of Lhx2 in the hematopoietic stem cell function, liver development and disease

    Author : Ewa Wandzioch; Leif Carlsson; Stephen A Duncan; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; liver fibrosis; liver development; Lhx2; hematopoietic stem cells; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; molecular cell biology; molekylär cellbiologi;

    Abstract : During embryonic development, generation of functional organs is dependent on proper interactions between different cell types. Elucidation of the mechanisms operating during organ formation might provide insights into the origin of many pathological disorders in the adult. READ MORE