Search for dissertations about: "human embryonic stem cells"

Showing result 21 - 25 of 155 swedish dissertations containing the words human embryonic stem cells.

  2. 21. Stem cells for cardiac regeneration

    Author : Ivana Bulatović; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Recent studies have demonstrated a turnover of cardiomyocytes throughout the adult life. Whether this regenerative potential is due to proliferation and differentiation of resident stem cells or to the dedifferentiation of adult cardiomyocytes remains unclear. READ MORE

  4. 22. Exploring Direct Conversion of Human Glia into Therapeutic Neurons

    Author : Jessica Giacomoni; Utvecklings- och regenerativ neurobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human embryonic stem cells; glial progenitor cells; neuronal reprogramming; induced neurons; spheroids; brain slice cultures; neurodegenerative disorders;

    Abstract : Direct neuronal reprogramming of a somatic cell into therapeutic neurons, without a transient pluripotent state, provides new promise for the large number of individuals afflicted by neurodegenerative diseases or brain injury. This approach could be potentially applied directly in the brain by targeting resident cells as a source of new neurons. READ MORE

  5. 23. Molecular mechanisms of embryonic stem cell pluripotency: transcription, telomere maintenance and proliferation

    Author : Dzeneta Vizlin-Hodzic; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; embryonic stem cells; Oct4; SAF-A; Brg1; Tpt1; Npm1; transcriptional regulation; cell proliferation; shelterin;

    Abstract : Somatic cell nuclear transfer and generation of induced pluripotent stem cells provide potential routes towards generation of patient specific embryonic stem (ES) cells. These procedures require induction of Oct4 gene expression, high telomerase activity and specific cell proliferation, characteristics shared with cancer stem cells. READ MORE

  6. 24. Pluripotent Circulations: Analyzing Articulations of Stem Cells in the USA, prior to 2001

    Author : Morten Sager; Göteborgs universitet; []
    Keywords : HUMANIORA; HUMANITIES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Actor-Network Theory; meta-theory; obligatory point of passage; boundary objects; sociotechnical reality; articulations; human embryonic stem cells; spare embryos; pluripotency;

    Abstract : In this thesis, stem cell research and politics in the USA are analyzed by using actor-network theory (ANT). Here ANT is put to work on largely textual materials, often directly from US political settings, such as Congressional debates and national panels. READ MORE

  7. 25. Human pluripotent stem cells : effects of handling and microenvironment

    Author : Frida Holm; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Pluripotent stem cells hold great promise in regenerative medicine and drug development due to their developmental potential towards multiple lineages. However, there are still hurdles to overcome before these cells are safe enough for clinical use even though attempts have already been initiated. READ MORE