Search for dissertations about: "human growth hormone"

Showing result 1 - 5 of 122 swedish dissertations containing the words human growth hormone.

  1. 1. Identification of novel growth hormone-regulated factors

    Author : Björn Andersson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : Growth hormone; idiopathic short stature; growth hormone deficient; prepubertal; children; genomic; proteomic;

    Abstract : The studies described in this thesis aimed to identify novel factors involved in the regulation of longitudinal growth and bone mineralization in response to growth hormone (GH) treatment. This was done by performing a single factor study (Paper I) where it was found that growth response was negatively correlated with adiponectin levels during the first year of GH treatment in short prepubertal children. READ MORE

  2. 2. Growth hormone responsiveness in children : results from Swedish multicenter clinical trials of growth hormone treatment

    Author : Elena Lundberg; Berit Kriström; Kerstin Albertsson-Wikland; Roland Pfäffle; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gain in height; puberty; IGHD; non-GHD; IGF-I; bioavailability;

    Abstract : The general aims of the thesis were to study GH responsiveness by estimation of pharmacokinetics and bioavailability of injected recombinant human GH (rhGH), of growth response as gain in heightSDS during childhood and puberty, and IGF-I response as change in circulating IGF-ISDS and IGFBP3SDS. Methods Short children were recruited during 1988–1999 into two national randomized multicentre clinical trials on growth until adult height. READ MORE

  3. 3. Growth Hormone and Anabolic Androgenic Steroids : Effects on Neurochemistry and Cognition

    Author : Alfhild Grönbladh; Mathias Hallberg; Jörgen Isgaard; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Growth hormone; anabolic androgenic steroids; nandrolone decanoate; insulin-like growth factor; GABAB; opioids; memory; water maze; autoradiography; central nervous system; rats; Biological Research on Drug Dependence; Biologisk beroendeforskning;

    Abstract : Growth hormone (GH) stimulates growth and metabolism but also displays profound effects on the central nervous system (CNS). GH affects neurogenesis and neuroprotection, and has been shown to counteract drug-induced apoptosis in the brain. READ MORE

  4. 4. Growth hormone and the heart in children

    Author : Anders Nygren; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Growth hormone secretion pattern; Cardiac dimensions; Growth hormone treatment;

    Abstract : Background and Aims: The fact that growth hormone (GH) influences cardiovascular structure and function is well established through both human and animal studies. Despite being secreted in a pulsatile fashion, only the impact of peak GH concentrations on cardiac parameters has previously been reported, and the time-dependency of cardiovascular effects during GH treatment has not been detailed. READ MORE

  5. 5. Monoclonal antibodies to human growth hormone : characterization, quantitation and isolation of hGH variants

    Author : Ingileif Jónsdóttir; Stockholms universitet; []
    Keywords : ;

    Abstract : .... READ MORE