Search for dissertations about: "human parasite thesis"

Showing result 1 - 5 of 117 swedish dissertations containing the words human parasite thesis.

  2. 1. Studies of Giardia-host interactions: role of cysteine-rich surface proteins

    Author : Dimitra Peirasmaki; Staffan Svärd; Steven Singer; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Giardia; intestinal parasite; parasite infection; host-parasite interaction; virulence factors; HCMPs; cysteine-rich proteins; secretome; proteome;

    Abstract : Giardia intestinalis is a eukaryotic parasite that colonizes the small intestine of humans and animals causing the diarrheal disease known as giardiasis. This parasite is not invasive and does not internalize into host cells but it rather attaches to the brush border surface of the small intestine disrupting the epithelial barrier. READ MORE

  4. 2. Leishmaniasis in Sweden. Molecular, diagnostic and epidemiological studies of the parasite Leishmania in a non-endemic country

    Author : Sara Karlsson Söbirk; Infektionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; leishmaniasis; Parasite; Epidemiological studies; Serology; diagnostic method; Immune System; Sweden; leishmaniasis; Leishmania; immune system; chitinase; CAZy; Immune evasion; Antimicrobial peptide AMP ; Chemokine; epidemiology; Sweden; Serological assays; diagnostic method;

    Abstract : This doctoral thesis consists of four separate papers, in which we; investigate epidemiological and clinical aspects of leishmaniasis in Sweden in order to increase awareness of the disease, elucidate some aspects of the interaction of the parasite and the human immune system and validate serological tools as a complement for diagnosis of leishmaniasis.. READ MORE

  5. 3. Causes and consequences of blood parasite infections in birds

    Author : Martin Stjernman; Biodiversitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Animal physiology; Djurfysiologi; Parasitologi människa och djur ; Parasitology human and animal ; maternal transfer; stabilising selection; parasite resistance; parasites; trade-off; cost of reproduction; Ficedula hypoleuca; pied flycatcher; Haemoproteus; blue tit; Parus caeruleus;

    Abstract : Parasites are ubiquitous and can cause significant fitness reductions to their hosts. Therefore, selection for the evolution of host resistance should be strong. However, resistance may be costly and should be traded-off against other fitness related traits. READ MORE

  6. 4. Inhibitors of Human and Malaria Parasite Dihydroorotate Dehydrogenase

    Author : Ingela Fritzson; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; DHODH; Synthesis; Inhibitors.; Dihydroorotate dehydrogenase;

    Abstract : In the first part of the PhD work, small chemical entities (fragments) found to inhibit human dihydroorotate dehydrogenase (DHODH), were chemically optimized. As part of an ample program at Active Biotech to find new drugs against autoimmune diseases, expanded fragments were repeatedly designed, synthesized and evaluated in a human DHODH assay. READ MORE

  7. 5. Parasite signalling and host responses in experimental and human African trypanosomiasis

    Author : Maha Hamadien; Karolinska Institutet; Karolinska Institutet; []
    Keywords : TLTF; anti-TLTF antibodies; IFN-gamma; Human African trypanosomiasis; T b. brucei; ;

    Abstract : African trypanosomiasis or sleeping sickness is a disease of tropical Africa caused by the unicellular-flagellated protozoan parasite, Trypanosoma brucei (T b.), which is transmitted by its insect vector, the tsetse fly. In humans, there are two forms of the disease: a chronic form in West and Central Africa, caused by T. b. READ MORE