Search for dissertations about: "human rotavirus"

Showing result 1 - 5 of 11 swedish dissertations containing the words human rotavirus.

  2. 1. Methods for Analysis of Disease Associated Genomic Sequence Variation

    Author : Lovisa Lovmar; Ann-Christine Syvänen; Pui-Yan Kwok; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Molecular medicine; microarray; molecular medicine; single nucleotide polymorphism; whole genome amplification; breast cancer; endometrial cancer; human rotavirus; Molekylärmedicin; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ;

    Abstract : In Molecular Medicine a wide range of methods are applied to analyze the genome to find genetic predictors of human disease. Apart from predisposing disease, genetic variations may also serve as genetic markers in the search for factors underlying complex diseases. READ MORE

  4. 2. Biochemical and epidemiological characterization of serogroup C rotavirus

    Author : Mikael Nilsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Rotaviruses are classified into seven serogroups (A-G) on the basis of antigenic and genetic properties. Group A rotavirus is the most common cause of diarrhea in infants and young children in both developing and developed countries. READ MORE

  5. 3. Host susceptibility to rotavirus infection and development of antibody-based immunotherapy

    Author : Gökçe Günaydın; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Rotavirus infects mature enterocytes of the small intestine of young children and cause gastroenteritis, leading to approximately 500 000 deaths annually worldwide, 85 % of which occur in the developing world. The main objectives of the thesis were to investigate host genetic factors leading to differential susceptibility to rotavirus infections and to develop an antibody-based oral therapy against the infections. READ MORE

  6. 4. Immune responses related to protection against rotavirus after natural infection and vaccination

    Author : Kari Johansen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Rotavirus is the most important cause of severe gastroenteritis in children under five years of age and is estimated to be responsible for one-third of all diarrhea-associated hospitalizations and 600,000 deaths/ year worldwide. 1500-1700 rotavirus-associated hospitalizations of children are estimated to occur annually in Sweden (3. READ MORE

  7. 5. Passive immunisation as therapy for gastrointestinal infections in children

    Author : Thomas Casswall; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Passive immunisation; treatment; bovine antibodies; chicken antibodies; rotavirus; Escherichia coli; ETEC; EPEC; Helicobacter pylori; clinical trials; infants; children;

    Abstract : Several prophylactic studies in animals and humans have shown potential efficacy of oral therapy with non-human antibodies against different pathogens. Passive immunisation with oral antibodies against different pathogens is an attractive way to treat different gastrointestinal infections caused by pathogens such as rotavirus or enteropathogenic and enterotoxigenic Escherichia coli (EPEC; ETEC). READ MORE