Search for dissertations about: "huntington"

Showing result 1 - 5 of 12 swedish dissertations containing the word huntington.

  2. 1. Molecular genetic studies on Huntington disease

    Author : Elisabeth Almqvist; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Huntington disease; PCR; predictive testing;

    Abstract : Huntington disease (HD) is an autosomal dominant neurodegenerative disorder associated with an expanded trinucleotide repeat (CAG). Prior to the gene identification in 1993, linkage analysis was used for predictive testing for at-risk individuals. READ MORE

  4. 2. On neural transplantation in a rat model of Huntington’s disease : a graft survival study

    Author : Ulrika Mundt-Petersen; Lund Neurologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cell survival; huntington disease; rat model; Huntington disease;

    Abstract : .... READ MORE

  5. 3. Mitochondrial dysfunction and metabolic intervention

    Author : Johannes Ehinger; Mitokondriell Medicin; []
    Keywords : Mitochondrial Diseases; Huntington Disease; Amyotrophic lateral sclerosis; Succinate; Neurodegenerative disease; Inborn errors of metabolism; Mitochondria; Animal models;

    Abstract : .... READ MORE

  6. 4. Pericytes in Neurodegeneration

    Author : Thomas Padel; Translationell Neurologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pericyte; Parkinson disease; Huntington Disease; PDGF-BB; RGS5;

    Abstract : .... READ MORE

  7. 5. Energy metabolism as a target for new treatment strategies in Huntington’s disease

    Author : Marie Sjögren; Biomarkörer vid hjärnsjukdomar; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Huntington´s disease; Energy metabolic alteration; Weight loss; Skeletal muscle; Adipose tissue; R6 2; Ghrelin; Liraglutide;

    Abstract : Huntington´s disease (HD) is a fatal inherited neurodegenerative disorder caused by a CAG triplet repeat expansion in the huntingtin (HTT) gene and characterized by cognitive and motoric dysfunctions as well as psychiatric problems. Accumulating evidence, however, suggests altered energy metabolism and a hyper-catabolic state as key features of HD pathology. READ MORE