Search for dissertations about: "hydroperoxide"

Showing result 21 - 25 of 28 swedish dissertations containing the word hydroperoxide.

  2. 21. Selenium Compounds in Milk. Studies of Selenoproteins, Selenium Enrichment and Oxidative Stability of Food

    Author : Tien Hoac; Tillämpad biokemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; metabolism; Biokemi; Metabolism; Biochemistry; Naturvetenskap; Natural science; Copper; Zinc; Oxidative stability; Thioredoxin reductase; Glutathione peroxidase; Selenoproteins; Milk; Selenium supplementation; Technological sciences; Teknik;

    Abstract : Selenium is an essential nutrient and in animals and humans it can either be specifically incorporated into proteins as selenocysteine or randomly as selenomethionine. It can also occur as low-molecular-weight compounds and the form of selenium in foods may also influence food quality. READ MORE

  4. 22. Studies on genetic hemochromatosis and the hepatotoxicity of iron

    Author : Karin Hagen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The aim of this study was to investigate the mutations and clinical expression of genetic hemochromatosis in patients and mechanisms involved in the hepatotoxicity of iron in animal and cell- culture models. In Swedish patients with a clinical diagnosis of genetic hemochromatosis, the C282Y mutation of the HFE gene was present in 94. READ MORE

  5. 23. Characterisation of the conserved Helicobacter pyloriproteins AhpC and HpaA

    Author : Anneli Maria Lundström; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Background: Infection with Helicobacter pylori gives rise to gastritis and may cause duodenal and gastric ulcers and gastric carcinoma in humans. The infection may induce an immune response against different antigens, among them a 26 kDa protein (AhpC) and a 29 kDa protein (HpaA). Aims: The aims were to characterise the 26 kDa and 29 kDa H. READ MORE

  6. 24. Structure and function of hepatic cytochromes P450 : implications for drug development

    Author : Mats Hidestrand; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Prediction of human drug metabolism in vivo by use of in vitro systems is of immense importance in drug development since it allows avoidance of drugs coming out on the market that are subjected to interindividual variability in metabolism or causes drug-drug interactions, both of which in turn can lead to adverse drug reactions and result in non-optimal treatment. In the present investigations the importance of P450 haplotype on substrate specificity was studied as well as a comparison of different in vitro systems for optimal prediction of in vivo drug metabolism. READ MORE

  7. 25. mPGES-1 : a key regulator of fever and neonatal respiratory depression

    Author : Sipra Saha; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Prostaglandins are potent lipid mediators, synthesized de novo from arachidonic acid (AA) upon cell activation. AA is oxidized by the cyclooxygenase isoenzymes (COX-1 and COX-2) to form PGH2, the common substrate for downstream enzymes involved in prostaglandin biosynthesis. READ MORE