Search for dissertations about: "hydroxysteroid 11-beta dehydrogenase 1"
Showing result 1 - 5 of 8 swedish dissertations containing the words hydroxysteroid 11-beta dehydrogenase 1.
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1. Personality and the HPA-axis in Association with Postpartum Depression
Abstract : Postpartum depression is a psychiatric disorder affecting a substantial proportion of newly delivered women, and remains a significant cause of childbirth-related morbidity. The aim of the present thesis was to examine psychological, endocrine and genetic aspects of postpartum depression in a large, population-based sample of women in Uppsala, Sweden. READ MORE
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2. Glucocorticoid administration : studies on weight regulation and metabolic implications
Abstract : Long-term treatment with glucocorticoids induces weight gain and increased risk to develop obesity-related metabolic complications like insulin resistance, type 2 diabetes and cardiovascular disease. Glucocorticoids have been suggested to play a role in development of visceral fat accumulation. READ MORE
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3. Congenital adrenal hyperplasia, CYP21 deficiency, screening and clinical aspects
Abstract : Congenital adrenal hyperplasia (CAH) is a group of recessively inherited disorders. More than 90% of all cases of CAB are caused by 21-hydroxylase deficiency. This enzyme deficiency results in reduced ability to synthesize cortisol and aldosterone and at the same time increased secretion of androgens. READ MORE
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4. The metabolic syndrome : studies on thrifty genes
Abstract : The metabolic syndrome consists of a cluster of atherogenic risk factors that include insulin resistance, glucose intolerance, hyperglycemia, dyslipidemia, obesity and a procoagulant state with impaired fibrinolysis. Genetic factors might predispose to the metabolic syndrome while the increasing prevalence of visceral and abdominal obesity linked to the shift to more sedentary lifestyles exacerbates the manifestation. READ MORE
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5. Expression and purification of membrane proteins: Focus on the G-protein coupled receptor MC4r
Abstract : Membrane proteins are crucial components of the cell and are involved in many biological processes. Recombinant overexpression systems together with different purification methods are necessary to obtain large amounts of purified receptor for biophysical and functional studies. READ MORE