Search for dissertations about: "hyperexcitability"
Showing result 1 - 5 of 16 swedish dissertations containing the word hyperexcitability.
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1. Mechanisms of Hyperexcitability in the Kindling Model of Epilepsy
Abstract : Epilepsy is a syndrome characterized by recurring attacks of sudden, excessive and synchronous discharge in populations of cerebral neurons. Kindling is an animal model for complex partial epilepsy, and is particularly useful for studies on the development of the abnormal excitability underlying the generation and spread of epileptic seizures. READ MORE
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2. Endogenous modulators of hyperexcitability in epilepsy: electrophysiological and optogenetic delineation of neuropeptide Y mechanisms in interneurons
Abstract : Epilepsy is one of the most common neurological disorders worldwide, affecting 1% of the general population, and is characterized by a predisposition for the generation of epileptic seizures. Despite having several different aetiologies, a common underlying cause of epilepsy seems to be an acquired imbalance between excitatory and inhibitory circuits in the brain, which leads to hyperexcitability and appearance of seizures. READ MORE
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3. Structure and function of trigeminal primary sensory neurons after peripheral nerve injury
Abstract : Iatrogenic injuries to branches of the trigeminal nerve are common during surgical procedures in the jaws and teeth, and as the repercussion of facial fractures or certain pathologies. A portion of these patients are left with disturbed sensory functions, and some with unpleasant abnormal sensations, including pain. READ MORE
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4. Pain influences somatosensory perception : an experimental and clinical study
Abstract : The underlying mechanisms maintaining long-term pain localised to musculoskeletal structures and joints are not infrequently unknown. In routine clinical work with such patients insufficient attention has been paid to phenomena indicating altered excitability of the central nervous system (CNS). READ MORE
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5. The analgesic mechanisms of buprenorphine
Abstract : Buprenorphine, a derivative of thebaine, is a semi-synthetic opiate and a partial p-opioid receptor agonist. Buprenorphine is also a weak kappa-opioid receptor antagonist. Buprenorphine is used clinically as an analgesic and for maintenance therapy of opiate-dependent subjects because it produces limited withdrawal symptoms. READ MORE