Search for dissertations about: "hyperglycemia"

Showing result 16 - 20 of 141 swedish dissertations containing the word hyperglycemia.

  1. 16. Systemic stress response and hyperglycemia after abdominal surgery in rat and man

    Author : Peter Hager; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Surgical trauma results in a complex neuroendocrine and metabolic response known as the systemic stress response, which is initiated by neuronal and humoral signals from the site of the injury. These signals converge at central sites and result in the activation of the hypothalamicpituitary-adrenal (HPA) axis, the sympathetic nervous system and an inflammatory response. READ MORE

  2. 17. Platelet dysfunction in diabetes mellitus : impact of hyperglycemia and glycoprotein GPIIb/IIIa inhibition

    Author : Masoud Razmara; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Diabetes mellitus (DM) is associated with increased cardiovascular morbidity and mortality, due to diabetic angiopathy. Hyperglycemia is one of the factors that may cause platelet dysfunction in diabetic patients. This work investigated mechanisms underlying hyperglycemia-induced platelet dysfunction, and its impact in DM patients. READ MORE

  3. 18. Stiffness and aneurysm of the aorta. Relations to vascular aging, hyperglycemia, and inflammation

    Author : Soumia Taimour; Vaskulära sjukdomar - kliniska studier; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Aortic stiffness; Hyperglycaemia; abdominal aortic aneurysm AAA ;

    Abstract : A well-functioning arterial system for the transport of oxygen to the cells is essential for human health. The aorta has a key role for the provision of this physiological effect. Disturbances to aortic function can lead to majorsymptoms and even death due to ruptured abdominal aortic aneurysm (AAA). READ MORE

  4. 19. Factors potentially influencing pathogenetic mechanisms and hyperglycemia in pre-diabetes and type 2 diabetes : clinical studies in humans

    Author : Henrik Wagner; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The pathogenetic mechanisms underlying type 2 diabetes (T2D) and prediabetes involve an interaction between β-cell dysfunction and insulin resistance (IR). The resulting hyperglycemia, as well as other clustered cardiovascular (CV) risk factors in T2D, constitutes a severe hazard for development of complications to the disease. READ MORE

  5. 20. Ischemic brain damage following transient and moderate compression of sensorimotor cortex in Sprague-Dawley and diabetic Goto-Kakizaki rats

    Author : Jurgita Kundrotiené; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Cortical compression; cerebral ischemia; neuroprotection; hyperglycemia; GotoKakizaki rats.;

    Abstract : Several animal models have been developed to facilitate the investigation of biochemical, physiological, and neurological events after cerebral ischemia. In this study we present a new animal model which reliably describes morphological changes and neurological deficits produced by mild to moderate brain ischemia and which can be used to identify novel, potentially useful, neuroprotective agents. READ MORE