Search for dissertations about: "hyperinsulinemia"
Showing result 1 - 5 of 46 swedish dissertations containing the word hyperinsulinemia.
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1. Islet hormonal hypersecretion and metformin’s effect on islet hormonal secretion studied in vitro and in vivo
Abstract : Childhood obesity has surged globally. Elevated levels of free fatty acids contribute to hyperinsulinemia, hyperproinsulinemia, and hyperglucagonemia connected with both obesity and type 2 diabetes mellitus (T2DM). Metformin has beneficial effects on islets by influencing metabolism and reducing stress-induced cell death. READ MORE
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2. Childhood Obesity and Islet Function
Abstract : The prevalence of childhood obesity and Type 2 Diabetes Mellitus (T2DM) has increased during recent decades. T2DM is accompanied with functional changes in the islets of Langerhans, which can be identified early in the pathogenesis. READ MORE
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3. Angiotensin II and vascular disease. Studies in rats and atherosclerosis-prone mice
Abstract : Angiotensin II (Ang II) is of importance for a number of physiological processes but also plays an important pathophysiological role in cardiovascular disease. The aim of this thesis was to evaluate the role of Ang II in hypertension-related atherosclerosis and vascular disease and to investigate possible anti-atherosclerotic effects of the angiotensin II, type 2 (AT2) receptor. READ MORE
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4. Leptin : a risk marker for cardiovascular disease
Abstract : A major cause of morbidity and early death in the Western societies is cardiovascular disease (CVD) secondary to atherosclerotic disease. Metabolic aberrations have been linked to CVD. READ MORE
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5. Novel properties of mature adipocytes in obesity and hyperinsulinemia
Abstract : Adipose tissue expansion and dysfunction, which leads to obesity and related metabolic diseases (e.g., diabetes and hypertension) are currently the most costly challenges for public health, yet the mechanisms underlying adipocyte functional dysregulation have not been fully elucidated . READ MORE