Search for dissertations about: "hyperinsulinemia"

Showing result 1 - 5 of 43 swedish dissertations containing the word hyperinsulinemia.

  1. 1. Angiotensin II and vascular disease. Studies in rats and atherosclerosis-prone mice

    Author : Maria E Johansson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : angiotensin II; atherosclerosis; AT1 receptor; AT2 receptor; blood pressure; hyperinsulinemia; hypertension; oxidative stress; salt; vascular disease; vascular function;

    Abstract : Angiotensin II (Ang II) is of importance for a number of physiological processes but also plays an important pathophysiological role in cardiovascular disease. The aim of this thesis was to evaluate the role of Ang II in hypertension-related atherosclerosis and vascular disease and to investigate possible anti-atherosclerotic effects of the angiotensin II, type 2 (AT2) receptor. READ MORE

  2. 2. Childhood Obesity and Islet Function

    Author : Johan Staaf; Peter Bergsten; Anders Forslund; Hindrik Mulder; Uppsala universitet; []
    Keywords : type 2 diabetes mellitus; Uppsala Longitudinal Study of Childhood Obesity; palmitate; glucose-stimulated insulin secretion; hyperinsulinemia; hyperglucagonemia; GLP-1; glicentin; magnetic resonance imaging; metabolic syndrome; oral glucose tolerance test; centroid; Pediatrik; Pediatrics;

    Abstract : The prevalence of childhood obesity and Type 2 Diabetes Mellitus (T2DM) has increased during recent decades. T2DM is accompanied with functional changes in the islets of Langerhans, which can be identified early in the pathogenesis. READ MORE

  3. 3. Leptin : a risk marker for cardiovascular disease

    Author : Stefan Söderberg; Ulf de Faire; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; leptin; testosterone; dysfibrinolysis; hyperinsulinemia; insulin resistance syndrome; menopause; cardiovascular disease; MONICA; epidemiology;

    Abstract : A major cause of morbidity and early death in the Western societies is cardiovascular disease (CVD) secondary to atherosclerotic disease. Metabolic aberrations have been linked to CVD. READ MORE

  4. 4. Novel properties of mature adipocytes in obesity and hyperinsulinemia

    Author : Qian Li; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Abstract : Adipose tissue expansion and dysfunction, which leads to obesity and related metabolic diseases (e.g., diabetes and hypertension) are currently the most costly challenges for public health, yet the mechanisms underlying adipocyte functional dysregulation have not been fully elucidated . READ MORE

  5. 5. Effects of prenatal IL-6 exposure and hyperinsulinemia on neuroendocrine regulation

    Author : Anne-Maj Samuelsson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : interleukin-6; intrauterine exposure; HPA-axis; RAS; hippocampus; spatial learning; hypertension; insulin signaling; cardiac hypertrophy;

    Abstract : Prenatal exposure to infection is associated with several neuroendocrine disorders. We therefore wanted to elucidate if cytokines, generated in response to maternal infection, play a key mechanistic role in this associations. READ MORE